KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
H1FOO
All Species:
10.3
Human Site:
S229
Identified Species:
17.44
UniProt:
Q8IZA3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZA3
NP_722575.1
346
35813
S229
D
K
A
M
R
A
P
S
S
A
G
G
L
S
R
Chimpanzee
Pan troglodytes
XP_001144407
346
35714
S229
D
K
A
M
R
A
P
S
S
A
G
G
L
S
R
Rhesus Macaque
Macaca mulatta
XP_001094128
336
35029
S219
D
K
A
I
Q
E
P
S
S
A
G
G
L
S
R
Dog
Lupus familis
XP_852262
323
34639
P203
D
K
A
T
Q
A
L
P
R
A
T
G
P
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIK3
304
32205
V193
A
K
A
K
P
K
E
V
R
K
A
P
L
K
Q
Rat
Rattus norvegicus
Q6P747
553
60788
E390
K
K
T
L
Q
K
C
E
K
N
G
W
L
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505393
294
31091
E183
K
A
V
V
G
E
K
E
P
V
G
Q
K
K
A
Chicken
Gallus gallus
Q5ZM33
559
61833
Y417
F
Q
L
C
F
P
Y
Y
P
S
P
D
V
L
Y
Frog
Xenopus laevis
P15308
273
29292
G162
K
T
E
K
E
P
K
G
E
K
T
K
A
V
A
Zebra Danio
Brachydanio rerio
NP_898894
257
26993
T146
D
P
N
E
P
K
A
T
K
P
K
K
E
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02255
256
26341
V145
K
K
V
Q
S
K
K
V
A
S
K
K
I
G
V
Honey Bee
Apis mellifera
XP_001121111
224
23571
G113
G
S
F
K
L
S
T
G
K
N
S
E
S
S
K
Nematode Worm
Caenorhab. elegans
P15796
191
19760
I80
V
G
D
Q
L
T
K
I
N
S
R
L
R
A
A
Sea Urchin
Strong. purpuratus
P15869
211
22150
Q100
K
E
G
K
S
D
A
Q
K
A
P
D
A
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
89.5
59.2
N.A.
45.9
22.6
N.A.
23.1
22
32.9
31.7
N.A.
29.4
28
25.7
32.3
Protein Similarity:
100
99.1
90.7
69.9
N.A.
54.9
34.7
N.A.
37.2
34.1
45
43
N.A.
43.6
39
38.4
44.2
P-Site Identity:
100
100
80
46.6
N.A.
20
20
N.A.
6.6
0
0
6.6
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
100
93.3
53.3
N.A.
26.6
40
N.A.
13.3
20
0
13.3
N.A.
26.6
20
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
36
0
0
22
15
0
8
36
8
0
15
15
29
% A
% Cys:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
36
0
8
0
0
8
0
0
0
0
0
15
0
0
0
% D
% Glu:
0
8
8
8
8
15
8
15
8
0
0
8
8
8
0
% E
% Phe:
8
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
8
0
0
15
0
0
36
29
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
8
0
0
0
0
8
0
0
% I
% Lys:
36
50
0
29
0
29
29
0
29
15
15
22
8
22
15
% K
% Leu:
0
0
8
8
15
0
8
0
0
0
0
8
36
8
0
% L
% Met:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
8
15
0
0
0
0
0
% N
% Pro:
0
8
0
0
15
15
22
8
15
8
15
8
8
0
0
% P
% Gln:
0
8
0
15
22
0
0
8
0
0
0
8
0
0
15
% Q
% Arg:
0
0
0
0
15
0
0
0
15
0
8
0
8
0
22
% R
% Ser:
0
8
0
0
15
8
0
22
22
22
8
0
8
36
0
% S
% Thr:
0
8
8
8
0
8
8
8
0
0
15
0
0
0
0
% T
% Val:
8
0
15
8
0
0
0
15
0
8
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _