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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: H1FOO All Species: 12.42
Human Site: S235 Identified Species: 21.03
UniProt: Q8IZA3 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZA3 NP_722575.1 346 35813 S235 P S S A G G L S R K A K A K G
Chimpanzee Pan troglodytes XP_001144407 346 35714 S235 P S S A G G L S R K A K A K G
Rhesus Macaque Macaca mulatta XP_001094128 336 35029 S225 P S S A G G L S R K A K A K G
Dog Lupus familis XP_852262 323 34639 S209 L P R A T G P S G K S K V K G
Cat Felis silvestris
Mouse Mus musculus Q8VIK3 304 32205 K199 E V R K A P L K Q D K A A G A
Rat Rattus norvegicus Q6P747 553 60788 E396 C E K N G W L E Q I S G K G F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505393 294 31091 K189 K E P V G Q K K A S L P P K A
Chicken Gallus gallus Q5ZM33 559 61833 L423 Y Y P S P D V L Y P E K Q Q D
Frog Xenopus laevis P15308 273 29292 V168 K G E K T K A V A K K A K E D
Zebra Danio Brachydanio rerio NP_898894 257 26993 K152 A T K P K K E K A T K A K G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P02255 256 26341 G151 K V A S K K I G V S S K K T A
Honey Bee Apis mellifera XP_001121111 224 23571 S119 T G K N S E S S K T K K V P H
Nematode Worm Caenorhab. elegans P15796 191 19760 A86 K I N S R L R A A L N K G V A
Sea Urchin Strong. purpuratus P15869 211 22150 A106 A Q K A P D A A K K A K L A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 89.5 59.2 N.A. 45.9 22.6 N.A. 23.1 22 32.9 31.7 N.A. 29.4 28 25.7 32.3
Protein Similarity: 100 99.1 90.7 69.9 N.A. 54.9 34.7 N.A. 37.2 34.1 45 43 N.A. 43.6 39 38.4 44.2
P-Site Identity: 100 100 100 46.6 N.A. 13.3 13.3 N.A. 13.3 6.6 6.6 0 N.A. 6.6 13.3 6.6 26.6
P-Site Similarity: 100 100 100 53.3 N.A. 20 26.6 N.A. 13.3 26.6 13.3 6.6 N.A. 33.3 20 26.6 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 8 36 8 0 15 15 29 0 29 22 29 8 36 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 15 0 0 0 8 0 0 0 0 15 % D
% Glu: 8 15 8 0 0 8 8 8 0 0 8 0 0 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 15 0 0 36 29 0 8 8 0 0 8 8 22 29 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 8 0 0 0 0 8 0 0 8 0 0 0 0 0 % I
% Lys: 29 0 29 15 15 22 8 22 15 43 29 65 29 36 0 % K
% Leu: 8 0 0 0 0 8 36 8 0 8 8 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 15 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 22 8 15 8 15 8 8 0 0 8 0 8 8 8 0 % P
% Gln: 0 8 0 0 0 8 0 0 15 0 0 0 8 8 0 % Q
% Arg: 0 0 15 0 8 0 8 0 22 0 0 0 0 0 0 % R
% Ser: 0 22 22 22 8 0 8 36 0 15 22 0 0 0 0 % S
% Thr: 8 8 0 0 15 0 0 0 0 15 0 0 0 8 0 % T
% Val: 0 15 0 8 0 0 8 8 8 0 0 0 15 8 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _