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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
H1FOO
All Species:
11.21
Human Site:
S246
Identified Species:
18.97
UniProt:
Q8IZA3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZA3
NP_722575.1
346
35813
S246
K
A
K
G
S
R
S
S
Q
G
D
A
E
A
Y
Chimpanzee
Pan troglodytes
XP_001144407
346
35714
S246
K
A
K
G
S
R
S
S
Q
G
D
A
E
A
Y
Rhesus Macaque
Macaca mulatta
XP_001094128
336
35029
S236
K
A
K
G
S
R
S
S
Q
G
D
A
E
A
C
Dog
Lupus familis
XP_852262
323
34639
S220
K
V
K
G
R
R
N
S
Q
G
G
E
T
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIK3
304
32205
A210
A
A
G
A
P
L
T
A
N
G
G
Q
K
V
K
Rat
Rattus norvegicus
Q6P747
553
60788
F407
G
K
G
F
S
G
T
F
Q
L
C
F
P
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505393
294
31091
K200
P
P
K
A
K
K
A
K
G
V
S
I
T
V
Q
Chicken
Gallus gallus
Q5ZM33
559
61833
E434
K
Q
Q
D
E
D
S
E
E
S
Q
E
E
E
E
Frog
Xenopus laevis
P15308
273
29292
K179
A
K
E
D
S
D
E
K
P
K
V
A
K
S
K
Zebra Danio
Brachydanio rerio
NP_898894
257
26993
K163
A
K
G
E
G
A
T
K
E
K
P
T
K
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02255
256
26341
A162
K
K
T
A
V
G
A
A
D
K
K
P
K
A
K
Honey Bee
Apis mellifera
XP_001121111
224
23571
K130
K
V
P
H
P
T
K
K
S
V
P
K
K
T
Q
Nematode Worm
Caenorhab. elegans
P15796
191
19760
L97
K
G
V
A
S
K
A
L
V
Q
S
V
G
N
G
Sea Urchin
Strong. purpuratus
P15869
211
22150
E117
K
L
A
A
K
K
K
E
A
K
E
K
K
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
89.5
59.2
N.A.
45.9
22.6
N.A.
23.1
22
32.9
31.7
N.A.
29.4
28
25.7
32.3
Protein Similarity:
100
99.1
90.7
69.9
N.A.
54.9
34.7
N.A.
37.2
34.1
45
43
N.A.
43.6
39
38.4
44.2
P-Site Identity:
100
100
93.3
46.6
N.A.
13.3
20
N.A.
6.6
20
13.3
0
N.A.
13.3
6.6
13.3
13.3
P-Site Similarity:
100
100
93.3
53.3
N.A.
33.3
26.6
N.A.
20
33.3
33.3
20
N.A.
33.3
13.3
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
29
8
36
0
8
22
15
8
0
0
29
0
36
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% C
% Asp:
0
0
0
15
0
15
0
0
8
0
22
0
0
0
0
% D
% Glu:
0
0
8
8
8
0
8
15
15
0
8
15
29
8
8
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
0
8
0
0
0
% F
% Gly:
8
8
22
29
8
15
0
0
8
36
15
0
8
0
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
65
29
36
0
15
22
15
29
0
29
8
15
43
8
29
% K
% Leu:
0
8
0
0
0
8
0
8
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
8
0
0
0
0
8
0
% N
% Pro:
8
8
8
0
15
0
0
0
8
0
15
8
8
0
0
% P
% Gln:
0
8
8
0
0
0
0
0
36
8
8
8
0
0
15
% Q
% Arg:
0
0
0
0
8
29
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
43
0
29
29
8
8
15
0
0
8
0
% S
% Thr:
0
0
8
0
0
8
22
0
0
0
0
8
15
8
0
% T
% Val:
0
15
8
0
8
0
0
0
8
15
8
8
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
22
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _