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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: H1FOO All Species: 7.88
Human Site: S260 Identified Species: 13.33
UniProt: Q8IZA3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZA3 NP_722575.1 346 35813 S260 Y R K T K A E S K S S K P T A
Chimpanzee Pan troglodytes XP_001144407 346 35714 S260 Y R K T K A E S K S S K P T A
Rhesus Macaque Macaca mulatta XP_001094128 336 35029 S250 C R K T T T G S K S S K P T A
Dog Lupus familis XP_852262 323 34639 R234 R K T K A G S R N S K S T I P
Cat Felis silvestris
Mouse Mus musculus Q8VIK3 304 32205 E224 K R S G S R Q E A N A H G K T
Rat Rattus norvegicus Q6P747 553 60788 F421 Y P S P G V L F P K K V S D G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505393 294 31091 G214 Q K P K G T K G A E G K G I T
Chicken Gallus gallus Q5ZM33 559 61833 E448 E E E S E E E E E S E E E E S
Frog Xenopus laevis P15308 273 29292 E193 K K D K E A K E V D K A N K E
Zebra Danio Brachydanio rerio NP_898894 257 26993 K177 K E T T D D A K P K T S E Q N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P02255 256 26341 K176 K K A V A T K K T A E N K K T
Honey Bee Apis mellifera XP_001121111 224 23571 V144 Q W V E K K T V S K K T A P A
Nematode Worm Caenorhab. elegans P15796 191 19760 V111 G A S G R F R V A E K A A A T
Sea Urchin Strong. purpuratus P15869 211 22150 E131 A R S K A K K E K L A A K K A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 89.5 59.2 N.A. 45.9 22.6 N.A. 23.1 22 32.9 31.7 N.A. 29.4 28 25.7 32.3
Protein Similarity: 100 99.1 90.7 69.9 N.A. 54.9 34.7 N.A. 37.2 34.1 45 43 N.A. 43.6 39 38.4 44.2
P-Site Identity: 100 100 73.3 6.6 N.A. 6.6 6.6 N.A. 6.6 13.3 6.6 6.6 N.A. 0 13.3 0 20
P-Site Similarity: 100 100 73.3 13.3 N.A. 26.6 6.6 N.A. 20 53.3 26.6 13.3 N.A. 20 13.3 6.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 22 22 8 0 22 8 15 22 15 8 36 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 8 8 0 0 0 8 0 0 0 8 0 % D
% Glu: 8 15 8 8 15 8 22 29 8 15 15 8 15 8 8 % E
% Phe: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 15 15 8 8 8 0 0 8 0 15 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % I
% Lys: 29 29 22 29 22 15 29 15 29 22 36 29 15 29 0 % K
% Leu: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 8 0 8 8 0 8 % N
% Pro: 0 8 8 8 0 0 0 0 15 0 0 0 22 8 8 % P
% Gln: 15 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % Q
% Arg: 8 36 0 0 8 8 8 8 0 0 0 0 0 0 0 % R
% Ser: 0 0 29 8 8 0 8 22 8 36 22 15 8 0 8 % S
% Thr: 0 0 15 29 8 22 8 0 8 0 8 8 8 22 29 % T
% Val: 0 0 8 8 0 8 0 15 8 0 0 8 0 0 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 22 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _