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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: H1FOO All Species: 13.03
Human Site: S308 Identified Species: 22.05
UniProt: Q8IZA3 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZA3 NP_722575.1 346 35813 S308 A P A K G S G S K V V P A H L
Chimpanzee Pan troglodytes XP_001144407 346 35714 S308 A P A K G S G S K V V P A H L
Rhesus Macaque Macaca mulatta XP_001094128 336 35029 S298 A P A K G S G S K V V P A H L
Dog Lupus familis XP_852262 323 34639 S283 A P P N G G R S K M L P E H L
Cat Felis silvestris
Mouse Mus musculus Q8VIK3 304 32205 A268 T V T V V Q G A E T V Q E T K
Rat Rattus norvegicus Q6P747 553 60788 M471 P Q G K T A S M K Q R G A K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505393 294 31091 N258 P K E L T A P N G L P K D K R
Chicken Gallus gallus Q5ZM33 559 61833 T493 S K P K P R K T P A A H Q G K
Frog Xenopus laevis P15308 273 29292 A237 K A E G G G K A K K E P P K A
Zebra Danio Brachydanio rerio NP_898894 257 26993 A221 A K A S K E G A E E P A T K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P02255 256 26341 A220 P K A V V A K A S K A K P A V
Honey Bee Apis mellifera XP_001121111 224 23571 K188 P K A A S E A K S M S K A K K
Nematode Worm Caenorhab. elegans P15796 191 19760 K155 G D K V K K A K S P K K I A K
Sea Urchin Strong. purpuratus P15869 211 22150 K175 A K K P A A K K A A A K P A P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 89.5 59.2 N.A. 45.9 22.6 N.A. 23.1 22 32.9 31.7 N.A. 29.4 28 25.7 32.3
Protein Similarity: 100 99.1 90.7 69.9 N.A. 54.9 34.7 N.A. 37.2 34.1 45 43 N.A. 43.6 39 38.4 44.2
P-Site Identity: 100 100 100 53.3 N.A. 13.3 20 N.A. 0 6.6 20 20 N.A. 6.6 13.3 0 6.6
P-Site Similarity: 100 100 100 66.6 N.A. 26.6 26.6 N.A. 20 20 26.6 33.3 N.A. 26.6 20 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 43 8 43 8 8 29 15 29 8 15 22 8 36 22 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % D
% Glu: 0 0 15 0 0 15 0 0 15 8 8 0 15 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 8 8 36 15 36 0 8 0 0 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 29 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 8 43 15 36 15 8 29 22 43 15 8 36 0 36 36 % K
% Leu: 0 0 0 8 0 0 0 0 0 8 8 0 0 0 29 % L
% Met: 0 0 0 0 0 0 0 8 0 15 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 29 29 15 8 8 0 8 0 8 8 15 36 22 0 15 % P
% Gln: 0 8 0 0 0 8 0 0 0 8 0 8 8 0 0 % Q
% Arg: 0 0 0 0 0 8 8 0 0 0 8 0 0 0 8 % R
% Ser: 8 0 0 8 8 22 8 29 22 0 8 0 0 0 0 % S
% Thr: 8 0 8 0 15 0 0 8 0 8 0 0 8 8 0 % T
% Val: 0 8 0 22 15 0 0 0 0 22 29 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _