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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: H1FOO All Species: 15.45
Human Site: S337 Identified Species: 26.15
UniProt: Q8IZA3 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZA3 NP_722575.1 346 35813 S337 L P I K A S S S K V S S Q R A
Chimpanzee Pan troglodytes XP_001144407 346 35714 S337 L P I K A S S S K V S S Q K A
Rhesus Macaque Macaca mulatta XP_001094128 336 35029 S327 L P I K A S S S K V S S Q R A
Dog Lupus familis XP_852262 323 34639 S312 M P T K S S S S K L A S R K A
Cat Felis silvestris
Mouse Mus musculus Q8VIK3 304 32205 A296 P I P R V R K A K T P E N T Q
Rat Rattus norvegicus Q6P747 553 60788 K516 R P A P S A V K K P S G S T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505393 294 31091 T286 P N S K G P L T K N S S K P A
Chicken Gallus gallus Q5ZM33 559 61833 G526 P A I K K P S G G S S S K K P
Frog Xenopus laevis P15308 273 29292 G265 E G A P V K A G K K G K K V T
Zebra Danio Brachydanio rerio NP_898894 257 26993 K249 S G A A A T E K A P G K R A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P02255 256 26341 K248 S A T A K K P K A K T T A A K
Honey Bee Apis mellifera XP_001121111 224 23571 K216 P K K A A A P K T V K S P A K
Nematode Worm Caenorhab. elegans P15796 191 19760 A183 A A P K K A P A K K A A A P K
Sea Urchin Strong. purpuratus P15869 211 22150 P203 A K K V A K K P A A K K A A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 89.5 59.2 N.A. 45.9 22.6 N.A. 23.1 22 32.9 31.7 N.A. 29.4 28 25.7 32.3
Protein Similarity: 100 99.1 90.7 69.9 N.A. 54.9 34.7 N.A. 37.2 34.1 45 43 N.A. 43.6 39 38.4 44.2
P-Site Identity: 100 93.3 100 53.3 N.A. 6.6 20 N.A. 33.3 33.3 6.6 6.6 N.A. 0 20 13.3 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 20 40 N.A. 46.6 46.6 20 20 N.A. 13.3 26.6 40 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 22 22 22 43 22 8 15 22 8 15 8 22 29 36 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 15 0 0 8 0 0 15 8 0 15 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 29 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 15 15 50 22 22 15 29 65 22 15 22 22 22 36 % K
% Leu: 22 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 8 0 0 8 0 0 % N
% Pro: 29 36 15 15 0 15 22 8 0 15 8 0 8 15 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 22 0 8 % Q
% Arg: 8 0 0 8 0 8 0 0 0 0 0 0 15 15 0 % R
% Ser: 15 0 8 0 15 29 36 29 0 8 43 50 8 0 8 % S
% Thr: 0 0 15 0 0 8 0 8 8 8 8 8 0 15 8 % T
% Val: 0 0 0 8 15 0 8 0 0 29 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _