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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RTKN2
All Species:
12.42
Human Site:
S245
Identified Species:
30.37
UniProt:
Q8IZC4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZC4
NP_660350.2
609
69304
S245
H
T
T
L
T
L
E
S
A
E
D
S
F
K
T
Chimpanzee
Pan troglodytes
XP_521685
727
81903
S342
H
T
T
L
T
L
E
S
A
E
D
S
F
K
T
Rhesus Macaque
Macaca mulatta
XP_001108982
563
62606
S239
S
L
D
S
A
G
G
S
G
S
S
P
I
L
L
Dog
Lupus familis
XP_536360
598
68211
F239
L
E
S
A
E
D
S
F
K
T
H
N
L
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q14B46
604
66943
N240
H
T
T
L
T
L
E
N
A
G
D
C
F
K
T
Rat
Rattus norvegicus
Q6V7V2
548
61135
P230
A
G
G
S
G
N
S
P
I
L
L
P
T
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510217
606
68399
S231
H
T
T
L
T
L
E
S
T
E
D
S
F
R
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5XGX5
612
69089
S244
Q
I
T
F
T
L
D
S
I
E
D
N
F
R
T
Zebra Danio
Brachydanio rerio
Q5XIZ9
642
72394
Q265
Y
T
T
L
G
L
E
Q
A
E
G
S
F
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001024370
515
57305
E203
L
S
I
A
D
A
C
E
E
A
T
I
H
N
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.2
38.4
85.3
N.A.
73
38.4
N.A.
75
N.A.
58.6
45
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
100
83.3
58.2
90.1
N.A.
85.2
57.4
N.A.
84.4
N.A.
75.1
65.1
N.A.
N.A.
N.A.
42
N.A.
P-Site Identity:
100
100
6.6
0
N.A.
80
0
N.A.
86.6
N.A.
53.3
60
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
6.6
13.3
N.A.
86.6
0
N.A.
93.3
N.A.
73.3
80
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
20
10
10
0
0
40
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
10
0
10
10
10
0
0
0
50
0
0
0
0
% D
% Glu:
0
10
0
0
10
0
50
10
10
50
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
10
0
0
0
0
60
0
0
% F
% Gly:
0
10
10
0
20
10
10
0
10
10
10
0
0
0
0
% G
% His:
40
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
20
0
0
10
10
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
0
0
30
0
% K
% Leu:
20
10
0
50
0
60
0
0
0
10
10
0
10
10
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
10
0
0
0
20
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
20
0
10
0
% P
% Gln:
10
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% R
% Ser:
10
10
10
20
0
0
20
50
0
10
10
40
0
10
10
% S
% Thr:
0
50
60
0
50
0
0
0
10
10
10
0
10
0
50
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _