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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COL27A1 All Species: 3.33
Human Site: S497 Identified Species: 5.64
UniProt: Q8IZC6 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZC6 NP_116277.2 1860 186892 S497 S P A P T P G S T R S T R P P
Chimpanzee Pan troglodytes XP_520208 1767 178013 Y510 P R P T S S G Y S F F H L A G
Rhesus Macaque Macaca mulatta XP_001097041 1232 122937 P414 V P A K V S R P A E K P I Q R
Dog Lupus familis XP_537089 1714 175790 P514 G P S G K R G P R G I P G P H
Cat Felis silvestris
Mouse Mus musculus Q5QNQ9 1845 186300 S494 S P V S Y L G S Q T L A P A L
Rat Rattus norvegicus Q80ZF0 1855 187793 S503 S S V S Y L G S Q T L A T A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505622 1712 167856 Y542 G R K G E L G Y P G R F G E K
Chicken Gallus gallus P02467 1362 129290 A481 R V G P I G P A G N R G E P G
Frog Xenopus laevis Q91717 1486 142245 G530 D G L A G P K G A P G E R G V
Zebra Danio Brachydanio rerio A0MSJ1 1658 168231 I488 P G R A P S G I K G D P G L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08120 1779 174282 P536 K L G R P G T P G A A G A P G
Honey Bee Apis mellifera XP_393523 1653 165523 G513 A G P R G E R G R E G P P G P
Nematode Worm Caenorhab. elegans P17139 1759 171068 M604 G I P G Y P G M K G E A G E I
Sea Urchin Strong. purpuratus NP_999674 1414 133005 A488 S A G S K G S A G E S G R P G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.1 64 44.4 N.A. 81 79.7 N.A. 32.2 30.9 33.5 53.2 N.A. 30 34.5 30.8 32.3
Protein Similarity: 100 91.7 65.1 57.4 N.A. 86 85.2 N.A. 40.9 40.4 42.6 65 N.A. 39.4 45.3 39 41
P-Site Identity: 100 6.6 13.3 20 N.A. 26.6 20 N.A. 6.6 13.3 13.3 6.6 N.A. 6.6 6.6 13.3 26.6
P-Site Similarity: 100 20 13.3 26.6 N.A. 26.6 20 N.A. 6.6 20 13.3 6.6 N.A. 13.3 13.3 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 15 15 0 0 0 15 15 8 8 22 8 22 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 0 0 8 8 0 0 0 22 8 8 8 15 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 8 8 0 0 0 % F
% Gly: 22 22 22 22 15 22 58 15 22 29 15 22 29 15 29 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % H
% Ile: 0 8 0 0 8 0 0 8 0 0 8 0 8 0 8 % I
% Lys: 8 0 8 8 15 0 8 0 15 0 8 0 0 0 8 % K
% Leu: 0 8 8 0 0 22 0 0 0 0 15 0 8 8 15 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 15 29 22 15 15 22 8 22 8 8 0 29 15 36 15 % P
% Gln: 0 0 0 0 0 0 0 0 15 0 0 0 0 8 0 % Q
% Arg: 8 15 8 15 0 8 15 0 15 8 15 0 22 0 8 % R
% Ser: 29 8 8 22 8 22 8 22 8 0 15 0 0 0 0 % S
% Thr: 0 0 0 8 8 0 8 0 8 15 0 8 8 0 0 % T
% Val: 8 8 15 0 8 0 0 0 0 0 0 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 22 0 0 15 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _