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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL3
All Species:
28.18
Human Site:
S258
Identified Species:
51.67
UniProt:
Q8IZE3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZE3
NP_065156.5
742
82857
S258
E
V
V
N
F
L
K
S
L
T
L
K
S
E
E
Chimpanzee
Pan troglodytes
XP_513987
742
82925
S258
E
V
V
N
F
L
K
S
L
T
L
K
S
E
E
Rhesus Macaque
Macaca mulatta
XP_001096051
736
82375
S258
E
V
V
N
F
L
K
S
L
T
L
K
S
E
E
Dog
Lupus familis
XP_537198
743
82483
S258
E
V
V
N
F
L
K
S
L
T
L
K
S
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBQ7
735
81315
S258
E
V
V
N
F
L
K
S
L
T
L
K
S
E
D
Rat
Rattus norvegicus
Q5M9F8
807
89107
E281
E
T
N
L
F
L
E
E
I
Q
I
K
E
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514536
1518
163635
S877
E
V
V
N
F
L
S
S
L
T
L
K
S
E
E
Chicken
Gallus gallus
NP_001012613
698
77220
P255
N
Q
L
V
F
A
E
P
V
A
V
K
S
F
L
Frog
Xenopus laevis
Q561M0
827
91284
E276
E
T
N
L
F
L
E
E
I
Q
I
K
D
P
A
Zebra Danio
Brachydanio rerio
NP_955951
768
85305
S258
D
I
M
N
F
L
K
S
L
T
L
K
N
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610175
683
77833
I242
L
R
P
R
L
S
A
I
L
L
H
P
Y
F
N
Honey Bee
Apis mellifera
XP_001123124
613
70111
Y173
Y
L
Q
R
I
R
K
Y
R
Y
E
K
A
I
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177952
810
89574
K264
D
I
M
S
F
L
H
K
L
V
L
K
S
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
85.5
N.A.
80.7
21.9
N.A.
31.8
61.9
21.8
51.9
N.A.
25.7
28.4
N.A.
33.5
Protein Similarity:
100
99.1
96.7
90.3
N.A.
87.7
38.5
N.A.
37.4
71.5
39
67.5
N.A.
45.9
49.7
N.A.
50.7
P-Site Identity:
100
100
100
100
N.A.
93.3
26.6
N.A.
93.3
20
26.6
73.3
N.A.
6.6
13.3
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
93.3
46.6
46.6
100
N.A.
6.6
26.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
0
0
8
0
0
8
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% D
% Glu:
62
0
0
0
0
0
24
16
0
0
8
0
8
62
47
% E
% Phe:
0
0
0
0
85
0
0
0
0
0
0
0
0
16
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% H
% Ile:
0
16
0
0
8
0
0
8
16
0
16
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
54
8
0
0
0
93
0
0
0
% K
% Leu:
8
8
8
16
8
77
0
0
70
8
62
0
0
0
8
% L
% Met:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
16
54
0
0
0
0
0
0
0
0
8
0
8
% N
% Pro:
0
0
8
0
0
0
0
8
0
0
0
8
0
16
0
% P
% Gln:
0
8
8
0
0
0
0
0
0
16
0
0
0
0
0
% Q
% Arg:
0
8
0
16
0
8
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
0
8
8
54
0
0
0
0
62
0
8
% S
% Thr:
0
16
0
0
0
0
0
0
0
54
0
0
0
0
0
% T
% Val:
0
47
47
8
0
0
0
0
8
8
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _