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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCYL3 All Species: 10
Human Site: Y312 Identified Species: 18.33
UniProt: Q8IZE3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZE3 NP_065156.5 742 82857 Y312 A V K S F L P Y L L G P K K D
Chimpanzee Pan troglodytes XP_513987 742 82925 Y312 A V K S F L P Y L L G P K K D
Rhesus Macaque Macaca mulatta XP_001096051 736 82375 H312 A V K S F L P H L L G P K K D
Dog Lupus familis XP_537198 743 82483 H312 A V K S F L P H L L G P K K D
Cat Felis silvestris
Mouse Mus musculus Q9DBQ7 735 81315 Y312 A V K S F L P Y L L G P K K E
Rat Rattus norvegicus Q5M9F8 807 89107 G338 L T P L F K V G K F L S A E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514536 1518 163635 H931 A V K S F L P H L L G P K Q G
Chicken Gallus gallus NP_001012613 698 77220 E304 K L F E V H E E H V R M V L L
Frog Xenopus laevis Q561M0 827 91284 M393 P H V V H G F M D T N P A I R
Zebra Danio Brachydanio rerio NP_955951 768 85305 H312 A V K S F L P H L L Q P K Q D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610175 683 77833 S291 F D E E V V A S Q L A C D L L
Honey Bee Apis mellifera XP_001123124 613 70111 F222 D V P S L L E F K Q F C K E N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001177952 810 89574 H318 A V N M L F P H L L T P R R E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 95.1 85.5 N.A. 80.7 21.9 N.A. 31.8 61.9 21.8 51.9 N.A. 25.7 28.4 N.A. 33.5
Protein Similarity: 100 99.1 96.7 90.3 N.A. 87.7 38.5 N.A. 37.4 71.5 39 67.5 N.A. 45.9 49.7 N.A. 50.7
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 6.6 N.A. 80 0 6.6 80 N.A. 6.6 26.6 N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 93.3 13.3 6.6 93.3 N.A. 20 46.6 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 62 0 0 0 0 0 8 0 0 0 8 0 16 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % C
% Asp: 8 8 0 0 0 0 0 0 8 0 0 0 8 0 39 % D
% Glu: 0 0 8 16 0 0 16 8 0 0 0 0 0 16 24 % E
% Phe: 8 0 8 0 62 8 8 8 0 8 8 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 8 0 0 47 0 0 0 8 % G
% His: 0 8 0 0 8 8 0 39 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 8 0 54 0 0 8 0 0 16 0 0 0 62 39 0 % K
% Leu: 8 8 0 8 16 62 0 0 62 70 8 0 0 16 16 % L
% Met: 0 0 0 8 0 0 0 8 0 0 0 8 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 8 % N
% Pro: 8 0 16 0 0 0 62 0 0 0 0 70 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 8 8 0 0 16 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 8 8 8 % R
% Ser: 0 0 0 62 0 0 0 8 0 0 0 8 0 0 0 % S
% Thr: 0 8 0 0 0 0 0 0 0 8 8 0 0 0 0 % T
% Val: 0 70 8 8 16 8 8 0 0 8 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 24 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _