KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NALCN
All Species:
23.03
Human Site:
S781
Identified Species:
56.3
UniProt:
Q8IZF0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZF0
NP_443099.1
1738
200331
S781
Q
R
I
S
R
G
K
S
L
E
T
L
T
Q
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095394
946
108944
K138
E
N
H
P
Y
F
D
K
P
L
F
I
V
G
R
Dog
Lupus familis
XP_542654
1767
203659
S810
Q
R
I
S
R
G
K
S
L
E
T
L
T
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXR5
1738
200423
S781
Q
R
I
S
R
G
K
S
L
E
T
L
T
Q
D
Rat
Rattus norvegicus
Q6Q760
1738
200472
S781
Q
R
I
S
R
G
K
S
L
E
T
L
T
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513665
1799
207525
S842
Q
R
I
S
R
G
K
S
L
E
T
L
T
Q
D
Chicken
Gallus gallus
XP_416967
1738
200228
S781
Q
R
I
S
R
G
K
S
L
E
T
L
T
Q
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001096981
2232
246987
R1105
R
S
I
R
R
S
V
R
S
G
S
I
K
L
K
Honey Bee
Apis mellifera
XP_393620
1258
145688
S450
V
V
R
L
I
K
A
S
P
M
L
E
D
F
V
Nematode Worm
Caenorhab. elegans
NP_741413
1861
215037
G828
F
N
M
Y
S
E
N
G
D
L
S
R
P
S
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
53.7
97.5
N.A.
98.6
98.7
N.A.
94.7
96.8
N.A.
N.A.
N.A.
44.6
41.9
44.2
N.A.
Protein Similarity:
100
N.A.
54
98
N.A.
99.3
99.2
N.A.
95.8
98.2
N.A.
N.A.
N.A.
56.8
54
61.7
N.A.
P-Site Identity:
100
N.A.
0
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
13.3
6.6
6.6
N.A.
P-Site Similarity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
33.3
6.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
10
0
0
0
10
0
70
% D
% Glu:
10
0
0
0
0
10
0
0
0
60
0
10
0
0
0
% E
% Phe:
10
0
0
0
0
10
0
0
0
0
10
0
0
10
0
% F
% Gly:
0
0
0
0
0
60
0
10
0
10
0
0
0
10
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
70
0
10
0
0
0
0
0
0
20
0
0
0
% I
% Lys:
0
0
0
0
0
10
60
10
0
0
0
0
10
0
10
% K
% Leu:
0
0
0
10
0
0
0
0
60
20
10
60
0
10
0
% L
% Met:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
20
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
20
0
0
0
10
0
0
% P
% Gln:
60
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% Q
% Arg:
10
60
10
10
70
0
0
10
0
0
0
10
0
0
10
% R
% Ser:
0
10
0
60
10
10
0
70
10
0
20
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
60
0
60
0
0
% T
% Val:
10
10
0
0
0
0
10
0
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _