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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IL28B All Species: 16.67
Human Site: S170 Identified Species: 73.33
UniProt: Q8IZI9 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZI9 NP_742151.2 200 22194 S170 Q E A P K K E S P G C L E A S
Chimpanzee Pan troglodytes XP_001135462 200 22157 S170 Q E A P K K E S P G C L E A S
Rhesus Macaque Macaca mulatta XP_001086865 200 22181 S170 Q E A P K K E S P G C L E A S
Dog Lupus familis XP_855366 360 39725 S330 H D A P E K E S L G C L E A S
Cat Felis silvestris
Mouse Mus musculus Q4VK74 193 21695 T163 Q E A Q S K E T P G C L E D S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517931 158 18129 I129 S Q E L Q R C I P Q A Q E S R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 93.5 42.2 N.A. 64.5 N.A. N.A. 41 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.5 95 47.2 N.A. 73.5 N.A. N.A. 55 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 73.3 N.A. 73.3 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 80 N.A. N.A. 40 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 84 0 0 0 0 0 0 0 17 0 0 67 0 % A
% Cys: 0 0 0 0 0 0 17 0 0 0 84 0 0 0 0 % C
% Asp: 0 17 0 0 0 0 0 0 0 0 0 0 0 17 0 % D
% Glu: 0 67 17 0 17 0 84 0 0 0 0 0 100 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 84 0 0 0 0 0 % G
% His: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 50 84 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 17 0 0 0 0 17 0 0 84 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 67 0 0 0 0 84 0 0 0 0 0 0 % P
% Gln: 67 17 0 17 17 0 0 0 0 17 0 17 0 0 0 % Q
% Arg: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 17 % R
% Ser: 17 0 0 0 17 0 0 67 0 0 0 0 0 17 84 % S
% Thr: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _