KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC5B
All Species:
10.91
Human Site:
T490
Identified Species:
24
UniProt:
Q8IZJ1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZJ1
NP_734465.2
945
103638
T490
K
V
Y
S
S
S
T
T
G
S
G
P
G
L
A
Chimpanzee
Pan troglodytes
XP_001164941
951
105434
K500
P
L
P
N
L
K
I
K
V
Y
N
T
S
G
A
Rhesus Macaque
Macaca mulatta
XP_001106162
1131
123665
T676
K
V
Y
S
S
S
T
T
G
S
G
P
G
L
A
Dog
Lupus familis
XP_850428
945
103644
T490
K
V
Y
N
S
G
T
T
G
S
G
P
G
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1S3
945
103720
I490
K
V
Y
N
S
S
T
I
G
S
G
S
G
L
A
Rat
Rattus norvegicus
O08722
945
103502
I490
K
V
Y
D
S
S
T
I
G
S
G
A
G
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q7T2Z5
931
102888
P473
T
N
S
P
I
L
D
P
L
P
N
L
K
I
K
Frog
Xenopus laevis
Q8JGT4
943
105065
S491
K
I
K
V
Y
N
S
S
T
V
G
S
S
P
G
Zebra Danio
Brachydanio rerio
NP_001104619
940
103131
S486
P
L
L
D
P
L
P
S
L
K
I
K
V
Y
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95TU8
1072
116399
G596
M
G
M
G
I
G
C
G
G
V
T
E
H
H
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q26261
919
101607
C455
R
A
A
L
I
Q
E
C
S
S
S
S
S
G
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.8
81.4
95.6
N.A.
92.3
91.8
N.A.
N.A.
63.7
78.8
66.9
N.A.
28.3
N.A.
27.9
N.A.
Protein Similarity:
100
77
81.9
98
N.A.
96.1
95.4
N.A.
N.A.
76.6
88.8
79.8
N.A.
43.1
N.A.
45.7
N.A.
P-Site Identity:
100
6.6
100
80
N.A.
80
80
N.A.
N.A.
0
13.3
0
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
20
100
86.6
N.A.
86.6
80
N.A.
N.A.
6.6
40
13.3
N.A.
6.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
0
0
0
0
10
0
0
46
% A
% Cys:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
0
19
0
10
55
0
55
0
46
19
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% H
% Ile:
0
10
0
0
28
0
10
19
0
0
10
0
0
10
0
% I
% Lys:
55
0
10
0
0
10
0
10
0
10
0
10
10
0
10
% K
% Leu:
0
19
10
10
10
19
0
0
19
0
0
10
0
46
0
% L
% Met:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
28
0
10
0
0
0
0
19
0
0
0
10
% N
% Pro:
19
0
10
10
10
0
10
10
0
10
0
28
0
10
10
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
19
46
37
10
19
10
55
10
28
28
0
10
% S
% Thr:
10
0
0
0
0
0
46
28
10
0
10
10
0
0
0
% T
% Val:
0
46
0
10
0
0
0
0
10
19
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
46
0
10
0
0
0
0
10
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _