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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TDH
All Species:
0
Human Site:
S219
Identified Species:
0
UniProt:
Q8IZJ6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZJ6
NULL
230
25407
S219
M
P
Q
S
M
A
N
S
S
A
T
W
K
P
A
Chimpanzee
Pan troglodytes
XP_519604
425
47803
P275
D
F
R
C
L
R
Y
P
G
I
I
S
A
D
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534558
403
44769
P253
D
F
R
C
L
R
Y
P
G
I
I
S
A
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3F7
373
41443
P223
D
F
R
C
L
R
Y
P
G
I
I
S
A
D
S
Rat
Rattus norvegicus
NP_001099514
373
41663
P223
D
F
R
C
L
R
Y
P
G
I
I
S
A
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506425
371
41309
P221
D
F
R
C
L
R
Y
P
G
I
I
S
A
D
S
Chicken
Gallus gallus
XP_420039
373
41506
P223
D
F
R
C
L
R
Y
P
G
I
I
S
A
D
S
Frog
Xenopus laevis
NP_001084635
373
41711
P223
D
F
R
C
L
R
Y
P
G
I
I
S
A
D
S
Zebra Danio
Brachydanio rerio
NP_998410
375
41629
P225
D
F
R
C
L
R
Y
P
G
I
I
S
A
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649230
367
41711
P213
D
F
R
C
L
R
F
P
G
V
I
S
S
D
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789391
373
41893
P213
D
F
R
S
L
R
L
P
G
V
I
S
G
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.3
N.A.
50.8
N.A.
48.2
48.5
N.A.
50.1
50.1
49.3
48.5
N.A.
34
N.A.
N.A.
32.7
Protein Similarity:
100
51.5
N.A.
53.3
N.A.
54.6
54.1
N.A.
55.5
55.5
54.6
54.1
N.A.
44.6
N.A.
N.A.
42.6
P-Site Identity:
100
0
N.A.
0
N.A.
0
0
N.A.
0
0
0
0
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
20
N.A.
20
N.A.
20
20
N.A.
20
20
20
20
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
10
0
0
73
0
10
% A
% Cys:
0
0
0
82
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
91
0
0
0
0
0
0
0
0
0
0
0
0
91
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
91
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
91
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
73
91
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
0
0
91
0
10
0
0
0
0
0
0
0
0
% L
% Met:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
91
0
0
0
0
0
10
10
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
91
0
0
91
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
19
0
0
0
10
10
0
0
91
10
0
73
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
73
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _