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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK20
All Species:
19.39
Human Site:
S280
Identified Species:
35.56
UniProt:
Q8IZL9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZL9
NP_001034892.1
346
38695
S280
P
H
Q
R
I
A
A
S
K
A
L
L
H
Q
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q5EDC3
243
27009
W203
L
P
R
H
W
I
C
W
V
N
S
F
S
T
L
Dog
Lupus familis
XP_533555
346
38425
S280
P
H
Q
R
I
S
A
S
Q
A
L
L
H
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHU3
346
38361
S280
P
R
Q
R
I
A
A
S
Q
A
L
L
H
Q
Y
Rat
Rattus norvegicus
Q4KM34
346
38431
S280
P
R
Q
R
I
A
A
S
Q
A
L
L
H
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507089
345
38509
A280
P
R
Q
R
I
P
A
A
Q
A
L
L
H
Q
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
P20911
352
39672
S293
P
C
A
R
C
T
A
S
Q
A
L
R
K
R
Y
Zebra Danio
Brachydanio rerio
A8WIP6
344
39006
R280
S
K
Q
R
I
S
A
R
Q
A
L
L
H
P
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624845
304
34829
I264
E
P
E
A
I
D
L
I
S
K
I
L
I
Y
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799108
346
39277
S288
S
R
Q
R
I
S
A
S
E
A
L
L
H
P
Y
Poplar Tree
Populus trichocarpa
XP_002317890
416
47261
Q286
P
K
T
R
I
T
V
Q
Q
A
L
E
H
R
Y
Maize
Zea mays
P23111
294
33816
A250
R
W
Q
A
Q
D
L
A
T
V
V
P
N
L
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LMT0
391
44511
K284
P
K
A
R
I
S
I
K
Q
A
L
E
H
R
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
57.5
93.3
N.A.
94.2
93.6
N.A.
84.9
N.A.
39.4
75.4
N.A.
N.A.
41.3
N.A.
69
Protein Similarity:
100
N.A.
60.6
97.1
N.A.
97.1
96.5
N.A.
93
N.A.
55.1
86.9
N.A.
N.A.
60.9
N.A.
82.9
P-Site Identity:
100
N.A.
0
86.6
N.A.
86.6
86.6
N.A.
73.3
N.A.
46.6
60
N.A.
N.A.
13.3
N.A.
66.6
P-Site Similarity:
100
N.A.
6.6
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
60
73.3
N.A.
N.A.
26.6
N.A.
80
Percent
Protein Identity:
40.1
38.1
N.A.
40.1
N.A.
N.A.
Protein Similarity:
54.3
55.2
N.A.
54.9
N.A.
N.A.
P-Site Identity:
46.6
6.6
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
60
26.6
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
16
0
24
62
16
0
77
0
0
0
0
0
% A
% Cys:
0
8
0
0
8
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
8
% D
% Glu:
8
0
8
0
0
0
0
0
8
0
0
16
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
16
0
8
0
0
0
0
0
0
0
0
70
0
0
% H
% Ile:
0
0
0
0
77
8
8
8
0
0
8
0
8
0
0
% I
% Lys:
0
24
0
0
0
0
0
8
8
8
0
0
8
0
0
% K
% Leu:
8
0
0
0
0
0
16
0
0
0
77
62
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
8
% N
% Pro:
62
16
0
0
0
8
0
0
0
0
0
8
0
16
0
% P
% Gln:
0
0
62
0
8
0
0
8
62
0
0
0
0
39
0
% Q
% Arg:
8
31
8
77
0
0
0
8
0
0
0
8
0
24
0
% R
% Ser:
16
0
0
0
0
31
0
47
8
0
8
0
8
0
0
% S
% Thr:
0
0
8
0
0
16
0
0
8
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
8
0
8
8
8
0
0
0
0
% V
% Trp:
0
8
0
0
8
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
77
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _