KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK20
All Species:
38.18
Human Site:
Y181
Identified Species:
70
UniProt:
Q8IZL9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZL9
NP_001034892.1
346
38695
Y181
L
L
Y
G
A
R
Q
Y
D
Q
G
V
D
L
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q5EDC3
243
27009
K105
P
L
A
Q
A
Q
V
K
S
Y
L
Q
M
L
L
Dog
Lupus familis
XP_533555
346
38425
Y181
L
L
Y
G
A
R
Q
Y
D
Q
G
V
D
L
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHU3
346
38361
Y181
L
L
Y
G
A
R
Q
Y
D
Q
G
V
D
L
W
Rat
Rattus norvegicus
Q4KM34
346
38431
Y181
L
L
Y
G
A
R
Q
Y
D
Q
G
V
D
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507089
345
38509
Y181
L
L
Y
G
A
R
Q
Y
D
E
G
V
D
L
W
Chicken
Gallus gallus
Frog
Xenopus laevis
P20911
352
39672
Y196
L
L
F
G
A
R
M
Y
G
V
G
V
D
M
W
Zebra Danio
Brachydanio rerio
A8WIP6
344
39006
Y181
L
L
Y
G
A
R
K
Y
D
E
G
V
D
L
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624845
304
34829
W167
S
H
Q
I
A
T
R
W
Y
R
A
P
E
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799108
346
39277
Y189
L
L
Y
G
A
R
K
Y
D
E
G
A
D
L
W
Poplar Tree
Populus trichocarpa
XP_002317890
416
47261
Y189
L
L
F
G
A
K
Q
Y
G
A
G
V
D
V
W
Maize
Zea mays
P23111
294
33816
R151
L
A
D
F
G
L
A
R
A
F
G
I
P
V
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LMT0
391
44511
Y187
L
L
F
G
A
K
Q
Y
G
A
A
V
D
V
W
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
57.5
93.3
N.A.
94.2
93.6
N.A.
84.9
N.A.
39.4
75.4
N.A.
N.A.
41.3
N.A.
69
Protein Similarity:
100
N.A.
60.6
97.1
N.A.
97.1
96.5
N.A.
93
N.A.
55.1
86.9
N.A.
N.A.
60.9
N.A.
82.9
P-Site Identity:
100
N.A.
20
100
N.A.
100
100
N.A.
93.3
N.A.
66.6
86.6
N.A.
N.A.
13.3
N.A.
80
P-Site Similarity:
100
N.A.
26.6
100
N.A.
100
100
N.A.
100
N.A.
80
100
N.A.
N.A.
40
N.A.
93.3
Percent
Protein Identity:
40.1
38.1
N.A.
40.1
N.A.
N.A.
Protein Similarity:
54.3
55.2
N.A.
54.9
N.A.
N.A.
P-Site Identity:
66.6
13.3
N.A.
60
N.A.
N.A.
P-Site Similarity:
86.6
26.6
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
93
0
8
0
8
16
16
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
54
0
0
0
77
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
24
0
0
8
0
0
% E
% Phe:
0
0
24
8
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
77
8
0
0
0
24
0
77
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
16
16
8
0
0
0
0
0
0
0
% K
% Leu:
85
85
0
0
0
8
0
0
0
0
8
0
0
70
16
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
8
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% P
% Gln:
0
0
8
8
0
8
54
0
0
31
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
62
8
8
0
8
0
0
0
0
8
% R
% Ser:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
8
0
70
0
24
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
77
% W
% Tyr:
0
0
54
0
0
0
0
77
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _