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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF654 All Species: 10.61
Human Site: S88 Identified Species: 38.89
UniProt: Q8IZM8 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZM8 NP_060763.2 581 65842 S88 F E N G N S D S K D L E V E T
Chimpanzee Pan troglodytes XP_526247 506 57289 E35 A G N L K R T E E Q Q G L D E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544797 1130 128197 N636 F E N G N S E N K N L E I E T
Cat Felis silvestris
Mouse Mus musculus Q9DAU9 571 65145 T88 F E N G N S N T K G L E I E T
Rat Rattus norvegicus XP_001063334 618 70805 T88 F E N G N S N T K S L E I E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515111 1161 131966 S673 F E N G K C D S S K E Q E M E
Chicken Gallus gallus XP_416639 805 91142 C314 E L E R S D V C P S L E N G G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.7 N.A. 47.6 N.A. 85.1 78.8 N.A. 31.4 40.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 71.2 N.A. 49.8 N.A. 90.1 85.1 N.A. 41 53.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 N.A. 73.3 N.A. 73.3 73.3 N.A. 40 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 N.A. 100 N.A. 93.3 93.3 N.A. 46.6 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 15 0 15 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 15 29 0 0 15 0 0 0 15 0 % D
% Glu: 15 72 15 0 0 0 15 15 15 0 15 72 15 58 29 % E
% Phe: 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 15 0 72 0 0 0 0 0 15 0 15 0 15 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 43 0 0 % I
% Lys: 0 0 0 0 29 0 0 0 58 15 0 0 0 0 0 % K
% Leu: 0 15 0 15 0 0 0 0 0 0 72 0 15 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % M
% Asn: 0 0 86 0 58 0 29 15 0 15 0 0 15 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 15 15 15 0 0 0 % Q
% Arg: 0 0 0 15 0 15 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 15 58 0 29 15 29 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 15 29 0 0 0 0 0 0 58 % T
% Val: 0 0 0 0 0 0 15 0 0 0 0 0 15 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _