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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC38A6
All Species:
8.48
Human Site:
T221
Identified Species:
18.67
UniProt:
Q8IZM9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZM9
NP_722518.1
456
50929
T221
W
S
I
P
C
P
L
T
L
N
Y
V
E
K
G
Chimpanzee
Pan troglodytes
XP_509991
412
46149
P186
V
F
P
L
A
L
L
P
K
I
G
F
L
G
Y
Rhesus Macaque
Macaca mulatta
XP_001097345
456
50960
T221
W
S
I
P
C
P
L
T
L
N
Y
V
E
K
C
Dog
Lupus familis
XP_852226
398
44217
Q172
I
Y
A
E
Q
Y
F
Q
I
S
N
A
T
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCP2
505
55573
E259
F
S
H
M
V
V
A
E
E
K
A
Q
L
Q
G
Rat
Rattus norvegicus
Q6WWW3
457
50173
T222
W
A
V
P
C
P
L
T
L
N
C
I
N
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510175
662
70569
P229
W
A
I
P
C
P
L
P
P
N
V
A
G
E
F
Chicken
Gallus gallus
Q5F468
501
55512
N259
I
I
N
A
T
L
I
N
A
T
L
A
P
F
A
Frog
Xenopus laevis
Q6DFE7
452
48963
V206
L
G
T
C
Y
V
T
V
V
V
V
V
R
C
I
Zebra Danio
Brachydanio rerio
Q503G8
449
49081
C213
V
K
K
W
S
I
P
C
P
L
P
I
N
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791177
465
51536
T221
P
N
G
S
L
E
N
T
L
E
D
Y
M
Y
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.8
96.7
77.6
N.A.
43.3
84.6
N.A.
53.6
43.3
24.7
56.7
N.A.
N.A.
N.A.
N.A.
44.7
Protein Similarity:
100
89.2
98
82.8
N.A.
59.5
90.5
N.A.
60.1
62.4
46
73
N.A.
N.A.
N.A.
N.A.
65.3
P-Site Identity:
100
6.6
93.3
0
N.A.
13.3
53.3
N.A.
46.6
0
6.6
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
6.6
93.3
13.3
N.A.
26.6
73.3
N.A.
60
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
10
10
10
0
10
0
10
0
10
28
0
10
10
% A
% Cys:
0
0
0
10
37
0
0
10
0
0
10
0
0
10
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
10
% D
% Glu:
0
0
0
10
0
10
0
10
10
10
0
0
19
10
0
% E
% Phe:
10
10
0
0
0
0
10
0
0
0
0
10
0
10
10
% F
% Gly:
0
10
10
0
0
0
0
0
0
0
10
0
10
10
19
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
19
10
28
0
0
10
10
0
10
10
0
19
0
0
10
% I
% Lys:
0
10
10
0
0
0
0
0
10
10
0
0
0
19
0
% K
% Leu:
10
0
0
10
10
19
46
0
37
10
10
0
19
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
10
0
0
0
10
10
0
37
10
0
19
0
0
% N
% Pro:
10
0
10
37
0
37
10
19
19
0
10
0
10
0
0
% P
% Gln:
0
0
0
0
10
0
0
10
0
0
0
10
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
28
0
10
10
0
0
0
0
10
0
0
0
10
0
% S
% Thr:
0
0
10
0
10
0
10
37
0
10
0
0
10
0
10
% T
% Val:
19
0
10
0
10
19
0
10
10
10
19
28
0
0
10
% V
% Trp:
37
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
10
10
0
0
0
0
19
10
0
10
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _