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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM10A4 All Species: 5.15
Human Site: S37 Identified Species: 9.44
UniProt: Q8IZP2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZP2 NP_003923 240 27407 S37 F L R E W V E S M G G T A T Q
Chimpanzee Pan troglodytes XP_001141005 369 41277 K41 W V E S M G V K V P P A T Q K
Rhesus Macaque Macaca mulatta XP_001102391 369 41316 K41 W V E S M G G K V P P A T Q K
Dog Lupus familis XP_851691 369 41409 K41 W V E S M G G K I P P A T H K
Cat Felis silvestris
Mouse Mus musculus Q99L47 371 41637 G40 E W V E S M G G K V P P A T H
Rat Rattus norvegicus P50503 368 41261 G40 E W V E S M G G K V P P A T H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLF0 361 40140 G39 R E W V E S M G G T I P P A P
Frog Xenopus laevis NP_001086657 376 41338 G39 T D W I I S M G A S V P A A S
Zebra Danio Brachydanio rerio NP_956063 362 39842 G37 F F K T W L L G M G A S I P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394645 378 42459 Q45 F I E F F G G Q I P K V N Q Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001196240 526 55041 M98 N S K R S E A M A A V S E G N
Poplar Tree Populus trichocarpa XP_002322119 385 42924 S37 F F K T Y L Q S L G A R F P P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93YR3 441 46603 S37 F F R D Y L E S L G A K I P T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.5 62.5 58.8 N.A. 57.9 57.3 N.A. N.A. 51.2 44.9 45.8 N.A. N.A. 28 N.A. 25.4
Protein Similarity: 100 61.2 64.2 61.7 N.A. 61.4 61.4 N.A. N.A. 58.4 52.3 55.5 N.A. N.A. 43.3 N.A. 33.6
P-Site Identity: 100 0 0 0 N.A. 20 20 N.A. N.A. 0 6.6 26.6 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 26.6 26.6 26.6 N.A. 26.6 26.6 N.A. N.A. 0 6.6 46.6 N.A. N.A. 33.3 N.A. 13.3
Percent
Protein Identity: 30.1 N.A. N.A. 27.2 N.A. N.A.
Protein Similarity: 42.6 N.A. N.A. 37.8 N.A. N.A.
P-Site Identity: 20 N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: 53.3 N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 16 8 24 24 31 16 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 16 8 31 24 8 8 16 0 0 0 0 0 8 0 0 % E
% Phe: 39 24 0 8 8 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 0 0 0 0 31 39 39 8 31 8 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 16 % H
% Ile: 0 8 0 8 8 0 0 0 16 0 8 0 16 0 0 % I
% Lys: 0 0 24 0 0 0 0 24 16 0 8 8 0 0 24 % K
% Leu: 0 8 0 0 0 24 8 0 16 0 0 0 0 0 0 % L
% Met: 0 0 0 0 24 16 16 8 16 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 31 39 31 8 24 16 % P
% Gln: 0 0 0 0 0 0 8 8 0 0 0 0 0 24 16 % Q
% Arg: 8 0 16 8 0 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 0 8 0 24 24 16 0 24 0 8 0 16 0 0 16 % S
% Thr: 8 0 0 16 0 0 0 0 0 8 0 8 24 24 8 % T
% Val: 0 24 16 8 0 8 8 0 16 16 16 8 0 0 0 % V
% Trp: 24 16 16 0 16 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 16 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _