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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM10A4 All Species: 28.48
Human Site: S72 Identified Species: 52.22
UniProt: Q8IZP2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZP2 NP_003923 240 27407 S72 L K A D E P S S E E S D L E I
Chimpanzee Pan troglodytes XP_001141005 369 41277 S76 L K A D E P S S E E S D L E I
Rhesus Macaque Macaca mulatta XP_001102391 369 41316 S76 L K A D E P S S E E S D L E I
Dog Lupus familis XP_851691 369 41409 S76 I K T D E P S S E E S D L E I
Cat Felis silvestris
Mouse Mus musculus Q99L47 371 41637 S75 I K T E E L S S E E S D L E I
Rat Rattus norvegicus P50503 368 41261 S75 I K T E E P S S E E S D L E I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLF0 361 40140 S74 V K S P E P E S E E S D L E I
Frog Xenopus laevis NP_001086657 376 41338 S74 T P P P K P E S E E S D I E I
Zebra Danio Brachydanio rerio NP_956063 362 39842 P72 K A A P K P E P A P P S E S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394645 378 42459 E80 P Q S E P E S E E E S D L E L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001196240 526 55041 I133 L H A K R A S I T C E F T E L
Poplar Tree Populus trichocarpa XP_002322119 385 42924 P72 E Y S D S K R P I E D D D E I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93YR3 441 46603 E72 D D M D E T E E V K P K V E E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.5 62.5 58.8 N.A. 57.9 57.3 N.A. N.A. 51.2 44.9 45.8 N.A. N.A. 28 N.A. 25.4
Protein Similarity: 100 61.2 64.2 61.7 N.A. 61.4 61.4 N.A. N.A. 58.4 52.3 55.5 N.A. N.A. 43.3 N.A. 33.6
P-Site Identity: 100 100 100 86.6 N.A. 73.3 80 N.A. N.A. 73.3 53.3 13.3 N.A. N.A. 46.6 N.A. 26.6
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 93.3 N.A. N.A. 86.6 66.6 20 N.A. N.A. 73.3 N.A. 33.3
Percent
Protein Identity: 30.1 N.A. N.A. 27.2 N.A. N.A.
Protein Similarity: 42.6 N.A. N.A. 37.8 N.A. N.A.
P-Site Identity: 33.3 N.A. N.A. 20 N.A. N.A.
P-Site Similarity: 40 N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 39 0 0 8 0 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 8 8 0 47 0 0 0 0 0 0 8 77 8 0 0 % D
% Glu: 8 0 0 24 62 8 31 16 70 77 8 0 8 93 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 24 0 0 0 0 0 0 8 8 0 0 0 8 0 70 % I
% Lys: 8 54 0 8 16 8 0 0 0 8 0 8 0 0 0 % K
% Leu: 31 0 0 0 0 8 0 0 0 0 0 0 62 0 16 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 8 8 24 8 62 0 16 0 8 16 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 24 0 8 0 62 62 0 0 70 8 0 8 0 % S
% Thr: 8 0 24 0 0 8 0 0 8 0 0 0 8 0 0 % T
% Val: 8 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _