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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM10A4 All Species: 6.97
Human Site: T25 Identified Species: 12.78
UniProt: Q8IZP2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZP2 NP_003923 240 27407 T25 K D P S I L H T Q E M R F L R
Chimpanzee Pan troglodytes XP_001141005 369 41277 R29 I L H T E E M R F L R E W V E
Rhesus Macaque Macaca mulatta XP_001102391 369 41316 R29 V L H T E E M R F L R E W V E
Dog Lupus familis XP_851691 369 41409 R29 V L H T E E M R F L R E W V E
Cat Felis silvestris
Mouse Mus musculus Q99L47 371 41637 M28 S V L H T E E M R F L R E W V
Rat Rattus norvegicus P50503 368 41261 M28 S V L H T E E M R F L R E W V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLF0 361 40140 E27 P G L L H T E E L G F L R E W
Frog Xenopus laevis NP_001086657 376 41338 E27 P D V L H C P E F K F L T D W
Zebra Danio Brachydanio rerio NP_956063 362 39842 L25 E N P S V L H L P E M S F F K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394645 378 42459 S33 I L N Q P E Y S T V K T F I E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001196240 526 55041 M86 S K E V T D E M Q D E A N S K
Poplar Tree Populus trichocarpa XP_002322119 385 42924 T25 A N P S I I H T P S L A F F K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93YR3 441 46603 T25 S D P S L L T T P S L S F F R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.5 62.5 58.8 N.A. 57.9 57.3 N.A. N.A. 51.2 44.9 45.8 N.A. N.A. 28 N.A. 25.4
Protein Similarity: 100 61.2 64.2 61.7 N.A. 61.4 61.4 N.A. N.A. 58.4 52.3 55.5 N.A. N.A. 43.3 N.A. 33.6
P-Site Identity: 100 0 0 0 N.A. 6.6 6.6 N.A. N.A. 0 6.6 46.6 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 20 20 20 N.A. 20 20 N.A. N.A. 0 13.3 73.3 N.A. N.A. 26.6 N.A. 20
Percent
Protein Identity: 30.1 N.A. N.A. 27.2 N.A. N.A.
Protein Similarity: 42.6 N.A. N.A. 37.8 N.A. N.A.
P-Site Identity: 40 N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: 66.6 N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 24 0 0 0 8 0 0 0 8 0 0 0 8 0 % D
% Glu: 8 0 8 0 24 47 31 16 0 16 8 24 16 8 31 % E
% Phe: 0 0 0 0 0 0 0 0 31 16 16 0 39 24 0 % F
% Gly: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % G
% His: 0 0 24 16 16 0 24 0 0 0 0 0 0 0 0 % H
% Ile: 16 0 0 0 16 8 0 0 0 0 0 0 0 8 0 % I
% Lys: 8 8 0 0 0 0 0 0 0 8 8 0 0 0 24 % K
% Leu: 0 31 24 16 8 24 0 8 8 24 31 16 0 8 0 % L
% Met: 0 0 0 0 0 0 24 24 0 0 16 0 0 0 0 % M
% Asn: 0 16 8 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 16 0 31 0 8 0 8 0 24 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 16 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 24 16 0 24 24 8 0 16 % R
% Ser: 31 0 0 31 0 0 0 8 0 16 0 16 0 8 0 % S
% Thr: 0 0 0 24 24 8 8 24 8 0 0 8 8 0 0 % T
% Val: 16 16 8 8 8 0 0 0 0 8 0 0 0 24 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 24 16 16 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _