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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM10A4
All Species:
39.39
Human Site:
Y234
Identified Species:
72.22
UniProt:
Q8IZP2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZP2
NP_003923
240
27407
Y234
I
A
E
H
Q
R
K
Y
E
R
K
R
E
E
_
Chimpanzee
Pan troglodytes
XP_001141005
369
41277
Y238
T
A
E
H
W
R
K
Y
E
R
K
H
E
E
R
Rhesus Macaque
Macaca mulatta
XP_001102391
369
41316
Y238
I
A
E
H
R
R
K
Y
E
R
K
R
E
E
R
Dog
Lupus familis
XP_851691
369
41409
Y238
I
A
E
H
R
R
K
Y
E
R
K
R
E
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q99L47
371
41637
Y237
I
A
E
H
R
R
K
Y
E
R
K
R
E
E
R
Rat
Rattus norvegicus
P50503
368
41261
Y237
I
A
E
H
R
R
K
Y
E
R
K
R
E
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLF0
361
40140
Y236
I
A
E
H
R
R
K
Y
E
R
K
R
E
E
K
Frog
Xenopus laevis
NP_001086657
376
41338
H236
I
A
E
H
R
R
K
H
E
R
K
R
E
E
K
Zebra Danio
Brachydanio rerio
NP_956063
362
39842
Y241
I
I
D
H
R
R
K
Y
E
R
K
R
E
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394645
378
42459
K242
I
E
E
H
K
R
K
K
E
R
K
I
Q
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196240
526
55041
Y295
I
V
E
H
K
R
K
Y
E
R
K
H
Q
E
R
Poplar Tree
Populus trichocarpa
XP_002322119
385
42924
Y241
I
E
E
H
R
R
K
Y
E
R
L
R
K
E
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93YR3
441
46603
Y247
L
E
E
H
R
R
K
Y
D
R
L
R
K
E
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.5
62.5
58.8
N.A.
57.9
57.3
N.A.
N.A.
51.2
44.9
45.8
N.A.
N.A.
28
N.A.
25.4
Protein Similarity:
100
61.2
64.2
61.7
N.A.
61.4
61.4
N.A.
N.A.
58.4
52.3
55.5
N.A.
N.A.
43.3
N.A.
33.6
P-Site Identity:
100
73.3
86.6
86.6
N.A.
86.6
86.6
N.A.
N.A.
86.6
80
73.3
N.A.
N.A.
60
N.A.
66.6
P-Site Similarity:
100
73.3
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
86.6
N.A.
N.A.
73.3
N.A.
80
Percent
Protein Identity:
30.1
N.A.
N.A.
27.2
N.A.
N.A.
Protein Similarity:
42.6
N.A.
N.A.
37.8
N.A.
N.A.
P-Site Identity:
66.6
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
80
N.A.
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
24
93
0
0
0
0
0
93
0
0
0
70
100
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
100
0
0
0
8
0
0
0
16
0
0
0
% H
% Ile:
85
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
16
0
100
8
0
0
85
0
16
0
24
% K
% Leu:
8
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
16
0
8
% Q
% Arg:
0
0
0
0
70
100
0
0
0
100
0
77
0
0
62
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% _