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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF113B All Species: 24.55
Human Site: S89 Identified Species: 33.75
UniProt: Q8IZP6 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZP6 NP_849192.1 322 36259 S89 G E E A A P E S L D V V Y R S
Chimpanzee Pan troglodytes XP_522704 322 36221 S89 G E E A A P E S L G V V Y R S
Rhesus Macaque Macaca mulatta XP_001089736 338 37838 S90 G E E A A P E S L G I V Y R S
Dog Lupus familis XP_538154 348 39406 S100 E E E N E S E S L G V V Y K S
Cat Felis silvestris
Mouse Mus musculus NP_079801 337 38041 S95 E E K A G N E S L G V V Y K S
Rat Rattus norvegicus NP_001004445 337 38010 S95 E E K A G N E S L G V V Y K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509909 347 38316 G99 G D E E E P P G L G V A Y R S
Chicken Gallus gallus NP_001004396 328 37759 E83 D D D D P S K E I G V T Y K S
Frog Xenopus laevis NP_001087087 319 36679 S80 E E E K S G K S I T V S Y K S
Zebra Danio Brachydanio rerio NP_001004536 321 36768 S83 E E E K E E K S V T V A Y K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650865 357 39775 K93 S S A S D D D K L G I A Y K S
Honey Bee Apis mellifera XP_001121039 282 32433 D74 T E T E K D K D A Q A L F E K
Nematode Worm Caenorhab. elegans O17917 384 43409 V75 D D N Q D I A V A T H S F A A
Sea Urchin Strong. purpuratus XP_001196290 326 37220 D75 S S E E E S K D T M V S Y K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX84 343 38691 P93 S T T T S G A P E R S V F H Y
Baker's Yeast Sacchar. cerevisiae P53769 259 29722 L54 K S G N S R T L Q L S H E N E
Red Bread Mold Neurospora crassa Q7SDY3 405 44422 Y114 Q I R S N T I Y E A D R D A A
Conservation
Percent
Protein Identity: 100 99 86.6 66.6 N.A. 67.9 67.9 N.A. 60.8 57 56.5 57.1 N.A. 40.3 48.4 31.7 43.5
Protein Similarity: 100 99.3 89.3 76.7 N.A. 78.3 78 N.A. 71.4 71.6 71.4 73.5 N.A. 57.4 63.9 45.8 63.1
P-Site Identity: 100 93.3 86.6 60 N.A. 60 60 N.A. 53.3 20 40 40 N.A. 20 6.6 0 26.6
P-Site Similarity: 100 93.3 93.3 66.6 N.A. 73.3 73.3 N.A. 60 53.3 66.6 60 N.A. 46.6 26.6 20 40
Percent
Protein Identity: N.A. N.A. N.A. 39.6 30.1 30.8
Protein Similarity: N.A. N.A. N.A. 57.1 48.1 45.4
P-Site Identity: N.A. N.A. N.A. 6.6 0 0
P-Site Similarity: N.A. N.A. N.A. 20 6.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 6 30 18 0 12 0 12 6 6 18 0 12 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 18 6 6 12 12 6 12 0 6 6 0 6 0 0 % D
% Glu: 30 53 48 18 24 6 36 6 12 0 0 0 6 6 6 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 18 0 0 % F
% Gly: 24 0 6 0 12 12 0 6 0 48 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 6 6 0 6 0 % H
% Ile: 0 6 0 0 0 6 6 0 12 0 12 0 0 0 0 % I
% Lys: 6 0 12 12 6 0 30 6 0 0 0 0 0 48 6 % K
% Leu: 0 0 0 0 0 0 0 6 48 6 0 6 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % M
% Asn: 0 0 6 12 6 12 0 0 0 0 0 0 0 6 0 % N
% Pro: 0 0 0 0 6 24 6 6 0 0 0 0 0 0 0 % P
% Gln: 6 0 0 6 0 0 0 0 6 6 0 0 0 0 0 % Q
% Arg: 0 0 6 0 0 6 0 0 0 6 0 6 0 24 0 % R
% Ser: 18 18 0 12 18 18 0 48 0 0 12 18 0 0 71 % S
% Thr: 6 6 12 6 0 6 6 0 6 18 0 6 0 0 0 % T
% Val: 0 0 0 0 0 0 0 6 6 0 59 42 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 6 0 0 0 0 71 0 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _