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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF113B All Species: 16.36
Human Site: T55 Identified Species: 22.5
UniProt: Q8IZP6 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZP6 NP_849192.1 322 36259 T55 S S G D E G D T V A Q P P R V
Chimpanzee Pan troglodytes XP_522704 322 36221 T55 S S G D E G D T V A Q P P R V
Rhesus Macaque Macaca mulatta XP_001089736 338 37838 A55 G S G D D G D A V A R P P R V
Dog Lupus familis XP_538154 348 39406 T53 S S S D E G S T V V R P E K K
Cat Felis silvestris
Mouse Mus musculus NP_079801 337 38041 S52 S S S D E G C S V V R P E K K
Rat Rattus norvegicus NP_001004445 337 38010 T52 S S S D E G C T V V R P E K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509909 347 38316 A58 S S S D E G S A V V R R E K R
Chicken Gallus gallus NP_001004396 328 37759 V43 S G E E G S T V V R K E R R R
Frog Xenopus laevis NP_001087087 319 36679 V49 R R I K K D V V N P M I Q K S
Zebra Danio Brachydanio rerio NP_001004536 321 36768 A45 S S G D E G S A V V R K K K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650865 357 39775 R56 A L V R A E N R R K R T N P N
Honey Bee Apis mellifera XP_001121039 282 32433 V43 S E E E S I T V S Y K S S R T
Nematode Worm Caenorhab. elegans O17917 384 43409 Q45 R R T N P M V Q S T K Q L D A
Sea Urchin Strong. purpuratus XP_001196290 326 37220 K44 V V R K E R K K T I S N P M K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX84 343 38691 S56 A D E E D G D S K S E S S I L
Baker's Yeast Sacchar. cerevisiae P53769 259 29722 N24 Q K K R Q K I N F S E E K L V
Red Bread Mold Neurospora crassa Q7SDY3 405 44422 D68 S D F E S S E D E A T G Q R I
Conservation
Percent
Protein Identity: 100 99 86.6 66.6 N.A. 67.9 67.9 N.A. 60.8 57 56.5 57.1 N.A. 40.3 48.4 31.7 43.5
Protein Similarity: 100 99.3 89.3 76.7 N.A. 78.3 78 N.A. 71.4 71.6 71.4 73.5 N.A. 57.4 63.9 45.8 63.1
P-Site Identity: 100 100 73.3 53.3 N.A. 46.6 53.3 N.A. 40 20 0 46.6 N.A. 0 13.3 0 13.3
P-Site Similarity: 100 100 86.6 66.6 N.A. 66.6 66.6 N.A. 53.3 33.3 13.3 60 N.A. 20 26.6 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 39.6 30.1 30.8
Protein Similarity: N.A. N.A. N.A. 57.1 48.1 45.4
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 20
P-Site Similarity: N.A. N.A. N.A. 60 26.6 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 6 0 0 18 0 24 0 0 0 0 6 % A
% Cys: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 0 48 12 6 24 6 0 0 0 0 0 6 0 % D
% Glu: 0 6 18 24 48 6 6 0 6 0 12 12 24 0 0 % E
% Phe: 0 0 6 0 0 0 0 0 6 0 0 0 0 0 0 % F
% Gly: 6 6 24 0 6 53 0 0 0 0 0 6 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 6 0 0 6 6 0 0 6 0 6 0 6 6 % I
% Lys: 0 6 6 12 6 6 6 6 6 6 18 6 12 36 24 % K
% Leu: 0 6 0 0 0 0 0 0 0 0 0 0 6 6 6 % L
% Met: 0 0 0 0 0 6 0 0 0 0 6 0 0 6 0 % M
% Asn: 0 0 0 6 0 0 6 6 6 0 0 6 6 0 6 % N
% Pro: 0 0 0 0 6 0 0 0 0 6 0 36 24 6 0 % P
% Gln: 6 0 0 0 6 0 0 6 0 0 12 6 12 0 0 % Q
% Arg: 12 12 6 12 0 6 0 6 6 6 42 6 6 36 12 % R
% Ser: 59 48 24 0 12 12 18 12 12 12 6 12 12 0 12 % S
% Thr: 0 0 6 0 0 0 12 24 6 6 6 6 0 0 6 % T
% Val: 6 6 6 0 0 0 12 18 53 30 0 0 0 0 24 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _