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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF113B
All Species:
40
Human Site:
Y147
Identified Species:
55
UniProt:
Q8IZP6
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZP6
NP_849192.1
322
36259
Y147
G
R
E
H
D
H
I
Y
R
G
I
H
S
Y
L
Chimpanzee
Pan troglodytes
XP_522704
322
36221
Y147
G
R
E
H
D
H
I
Y
R
G
I
H
S
Y
L
Rhesus Macaque
Macaca mulatta
XP_001089736
338
37838
Y148
G
R
E
H
D
Q
I
Y
R
G
I
N
S
Y
P
Dog
Lupus familis
XP_538154
348
39406
Y158
G
K
E
D
D
K
I
Y
R
G
I
N
N
Y
Q
Cat
Felis silvestris
Mouse
Mus musculus
NP_079801
337
38041
Y153
G
K
E
D
D
K
I
Y
R
G
I
N
N
Y
Q
Rat
Rattus norvegicus
NP_001004445
337
38010
Y153
G
K
E
D
D
K
I
Y
R
G
I
N
N
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509909
347
38316
Y157
G
K
E
D
D
G
I
Y
R
G
L
N
N
Y
P
Chicken
Gallus gallus
NP_001004396
328
37759
Y141
G
K
E
D
D
K
I
Y
R
G
I
N
N
Y
Q
Frog
Xenopus laevis
NP_001087087
319
36679
Y138
G
K
E
D
D
K
I
Y
R
G
I
H
N
Y
Q
Zebra Danio
Brachydanio rerio
NP_001004536
321
36768
Y141
G
K
E
D
D
K
I
Y
R
G
I
N
N
Y
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650865
357
39775
Y151
G
K
A
D
D
K
I
Y
R
G
I
N
N
Y
A
Honey Bee
Apis mellifera
XP_001121039
282
32433
P131
R
K
G
P
I
R
A
P
S
N
L
R
A
T
V
Nematode Worm
Caenorhab. elegans
O17917
384
43409
L132
V
E
K
D
G
K
I
L
Y
K
G
S
A
L
Y
Sea Urchin
Strong. purpuratus
XP_001196290
326
37220
Y133
G
V
A
D
D
K
K
Y
R
G
L
N
N
Y
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GX84
343
38691
G158
S
D
E
K
L
Y
K
G
I
H
G
Y
T
D
H
Baker's Yeast
Sacchar. cerevisiae
P53769
259
29722
V111
P
S
D
D
N
E
L
V
L
N
M
S
G
K
N
Red Bread Mold
Neurospora crassa
Q7SDY3
405
44422
E177
D
D
A
V
Q
N
S
E
R
E
P
D
G
T
Y
Conservation
Percent
Protein Identity:
100
99
86.6
66.6
N.A.
67.9
67.9
N.A.
60.8
57
56.5
57.1
N.A.
40.3
48.4
31.7
43.5
Protein Similarity:
100
99.3
89.3
76.7
N.A.
78.3
78
N.A.
71.4
71.6
71.4
73.5
N.A.
57.4
63.9
45.8
63.1
P-Site Identity:
100
100
80
60
N.A.
60
60
N.A.
53.3
60
66.6
60
N.A.
53.3
0
6.6
40
P-Site Similarity:
100
100
86.6
80
N.A.
80
80
N.A.
80
80
80
80
N.A.
73.3
26.6
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.6
30.1
30.8
Protein Similarity:
N.A.
N.A.
N.A.
57.1
48.1
45.4
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
18
0
0
0
6
0
0
0
0
0
12
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
12
6
65
71
0
0
0
0
0
0
6
0
6
0
% D
% Glu:
0
6
65
0
0
6
0
6
0
6
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
71
0
6
0
6
6
0
6
0
71
12
0
12
0
0
% G
% His:
0
0
0
18
0
12
0
0
0
6
0
18
0
0
18
% H
% Ile:
0
0
0
0
6
0
71
0
6
0
59
0
0
0
0
% I
% Lys:
0
53
6
6
0
53
12
0
0
6
0
0
0
6
0
% K
% Leu:
0
0
0
0
6
0
6
6
6
0
18
0
0
6
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% M
% Asn:
0
0
0
0
6
6
0
0
0
12
0
53
53
0
6
% N
% Pro:
6
0
0
6
0
0
0
6
0
0
6
0
0
0
12
% P
% Gln:
0
0
0
0
6
6
0
0
0
0
0
0
0
0
30
% Q
% Arg:
6
18
0
0
0
6
0
0
77
0
0
6
0
0
0
% R
% Ser:
6
6
0
0
0
0
6
0
6
0
0
12
18
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
6
12
0
% T
% Val:
6
6
0
6
0
0
0
6
0
0
0
0
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
6
0
71
6
0
0
6
0
71
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _