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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF113B
All Species:
42.73
Human Site:
Y235
Identified Species:
58.75
UniProt:
Q8IZP6
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZP6
NP_849192.1
322
36259
Y235
R
E
L
E
E
G
R
Y
C
I
C
E
D
E
N
Chimpanzee
Pan troglodytes
XP_522704
322
36221
Y235
R
E
L
E
E
G
R
Y
C
I
C
E
D
E
N
Rhesus Macaque
Macaca mulatta
XP_001089736
338
37838
Y236
R
E
L
E
E
G
R
Y
G
I
C
Q
D
E
N
Dog
Lupus familis
XP_538154
348
39406
Y246
R
E
L
D
E
G
R
Y
G
V
Y
E
D
E
N
Cat
Felis silvestris
Mouse
Mus musculus
NP_079801
337
38041
Y241
R
E
L
D
E
G
R
Y
G
V
Y
E
D
E
N
Rat
Rattus norvegicus
NP_001004445
337
38010
Y241
R
E
L
D
E
G
R
Y
G
V
Y
E
D
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509909
347
38316
Y245
R
E
L
D
E
G
R
Y
G
L
N
D
D
E
N
Chicken
Gallus gallus
NP_001004396
328
37759
Y229
R
E
L
D
E
G
R
Y
G
V
N
D
E
E
N
Frog
Xenopus laevis
NP_001087087
319
36679
Y226
R
E
L
E
E
G
R
Y
G
A
N
D
E
E
N
Zebra Danio
Brachydanio rerio
NP_001004536
321
36768
Y229
R
E
L
E
E
G
R
Y
G
A
N
D
D
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650865
357
39775
T239
M
D
H
E
N
Q
R
T
G
D
V
D
S
D
G
Honey Bee
Apis mellifera
XP_001121039
282
32433
D219
I
C
R
N
S
F
T
D
P
V
V
T
K
C
K
Nematode Worm
Caenorhab. elegans
O17917
384
43409
Y220
E
E
Y
E
A
G
K
Y
G
A
E
D
D
A
N
Sea Urchin
Strong. purpuratus
XP_001196290
326
37220
Y221
K
E
W
D
D
G
K
Y
Q
K
Q
Q
D
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GX84
343
38691
K245
K
E
W
E
E
A
E
K
V
R
K
R
N
K
A
Baker's Yeast
Sacchar. cerevisiae
P53769
259
29722
F197
L
D
L
E
K
I
P
F
K
C
T
L
C
K
E
Red Bread Mold
Neurospora crassa
Q7SDY3
405
44422
K266
K
E
W
E
N
V
T
K
G
K
K
N
L
Q
G
Conservation
Percent
Protein Identity:
100
99
86.6
66.6
N.A.
67.9
67.9
N.A.
60.8
57
56.5
57.1
N.A.
40.3
48.4
31.7
43.5
Protein Similarity:
100
99.3
89.3
76.7
N.A.
78.3
78
N.A.
71.4
71.6
71.4
73.5
N.A.
57.4
63.9
45.8
63.1
P-Site Identity:
100
100
86.6
73.3
N.A.
73.3
73.3
N.A.
66.6
60
66.6
73.3
N.A.
13.3
0
40
26.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
86.6
N.A.
86.6
86.6
80
80
N.A.
33.3
6.6
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.6
30.1
30.8
Protein Similarity:
N.A.
N.A.
N.A.
57.1
48.1
45.4
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
40
40
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
6
6
0
0
0
18
0
0
0
6
6
% A
% Cys:
0
6
0
0
0
0
0
0
12
6
18
0
6
6
0
% C
% Asp:
0
12
0
36
6
0
0
6
0
6
0
36
59
6
0
% D
% Glu:
6
83
0
59
65
0
6
0
0
0
6
30
12
59
6
% E
% Phe:
0
0
0
0
0
6
0
6
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
71
0
0
65
0
0
0
0
0
12
% G
% His:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
0
0
0
0
6
0
0
0
18
0
0
0
0
0
% I
% Lys:
18
0
0
0
6
0
12
12
6
12
12
0
6
12
6
% K
% Leu:
6
0
65
0
0
0
0
0
0
6
0
6
6
0
0
% L
% Met:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
6
12
0
0
0
0
0
24
6
6
0
65
% N
% Pro:
0
0
0
0
0
0
6
0
6
0
0
0
0
6
0
% P
% Gln:
0
0
0
0
0
6
0
0
6
0
6
12
0
6
0
% Q
% Arg:
59
0
6
0
0
0
65
0
0
6
0
6
0
0
0
% R
% Ser:
0
0
0
0
6
0
0
0
0
0
0
0
6
0
6
% S
% Thr:
0
0
0
0
0
0
12
6
0
0
6
6
0
0
0
% T
% Val:
0
0
0
0
0
6
0
0
6
30
12
0
0
0
0
% V
% Trp:
0
0
18
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
6
0
0
0
0
71
0
0
18
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _