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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYOCD All Species: 4.55
Human Site: S645 Identified Species: 14.29
UniProt: Q8IZQ8 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZQ8 NP_001139785.1 938 101997 S645 S P L G A V K S P Q H I S L P
Chimpanzee Pan troglodytes XP_001163626 938 101910 S645 S P L G A V K S P Q H I S L P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546628 935 100533 L642 C S P Q H S P L G A V K S P Q
Cat Felis silvestris
Mouse Mus musculus Q8VIM5 935 101355 K642 H S P L G G L K S P Q H I S L
Rat Rattus norvegicus Q8R5I7 938 101853 K645 H S P L G T L K S P Q H I S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518898 868 90549 A580 A G G Q L R P A Q Q L T R S Q
Chicken Gallus gallus NP_001074184 908 98752 G616 S D K L S N C G V P Q L S H I
Frog Xenopus laevis Q8AYC1 1067 117075 A719 V Q L S M V Q A Q P H T V N P
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 N.A. 84.7 N.A. 83 83.3 N.A. 40.6 68.4 32.4 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 N.A. 89.1 N.A. 88.1 88.6 N.A. 52.6 78.5 46 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 6.6 N.A. 0 0 N.A. 6.6 13.3 26.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 6.6 N.A. 0 0 N.A. 20 26.6 40 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 0 25 0 0 25 0 13 0 0 0 0 0 % A
% Cys: 13 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % C
% Asp: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 13 13 25 25 13 0 13 13 0 0 0 0 0 0 % G
% His: 25 0 0 0 13 0 0 0 0 0 38 25 0 13 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 25 25 0 13 % I
% Lys: 0 0 13 0 0 0 25 25 0 0 0 13 0 0 0 % K
% Leu: 0 0 38 38 13 0 25 13 0 0 13 13 0 25 25 % L
% Met: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 13 0 0 0 0 0 0 0 13 0 % N
% Pro: 0 25 38 0 0 0 25 0 25 50 0 0 0 13 38 % P
% Gln: 0 13 0 25 0 0 13 0 25 38 38 0 0 0 25 % Q
% Arg: 0 0 0 0 0 13 0 0 0 0 0 0 13 0 0 % R
% Ser: 38 38 0 13 13 13 0 25 25 0 0 0 50 38 0 % S
% Thr: 0 0 0 0 0 13 0 0 0 0 0 25 0 0 0 % T
% Val: 13 0 0 0 0 38 0 0 13 0 13 0 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _