KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA2D3
All Species:
24.24
Human Site:
S812
Identified Species:
48.48
UniProt:
Q8IZS8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZS8
NP_060868.2
1091
123011
S812
Q
L
L
D
E
R
K
S
P
V
V
A
A
V
G
Chimpanzee
Pan troglodytes
XP_516539
1091
123063
S812
Q
L
L
D
E
R
K
S
P
V
V
A
A
V
G
Rhesus Macaque
Macaca mulatta
XP_001082066
691
78292
D426
T
Q
I
S
T
L
A
D
V
Q
E
N
V
M
E
Dog
Lupus familis
XP_533789
1128
128284
S849
Q
L
L
D
E
R
K
S
P
V
V
A
A
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1L5
1091
122759
S812
Q
L
L
D
E
R
K
S
P
V
V
A
A
V
G
Rat
Rattus norvegicus
Q8CFG5
1085
122186
S806
Q
L
L
D
E
R
K
S
P
V
V
A
A
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520798
808
90331
S543
K
P
K
P
N
Y
N
S
V
D
L
S
E
L
E
Chicken
Gallus gallus
XP_414338
1090
123764
S811
Q
L
L
D
D
R
K
S
P
V
V
A
A
V
G
Frog
Xenopus laevis
NP_001079180
394
44696
L129
K
H
E
F
D
A
D
L
Q
Y
E
Y
F
N
A
Zebra Danio
Brachydanio rerio
XP_696635
1094
123822
A806
V
S
V
S
K
K
T
A
V
A
G
A
I
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610902
1218
140030
I891
A
G
E
S
N
S
E
I
L
V
T
A
S
H
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34374
1249
144358
D951
S
G
F
E
F
A
Y
D
H
V
V
D
T
M
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
63.3
90.4
N.A.
98
97.3
N.A.
49.2
92.4
31.1
55.6
N.A.
32.8
N.A.
22.8
N.A.
Protein Similarity:
100
98.6
63.3
92.1
N.A.
98.2
97.8
N.A.
61.2
95.3
33
74.4
N.A.
51.8
N.A.
41.8
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
6.6
93.3
0
6.6
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
33.3
100
13.3
33.3
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
17
9
9
0
9
0
67
50
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
50
17
0
9
17
0
9
0
9
0
0
0
% D
% Glu:
0
0
17
9
42
0
9
0
0
0
17
0
9
0
17
% E
% Phe:
0
0
9
9
9
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
17
0
0
0
0
0
0
0
0
9
0
0
9
50
% G
% His:
0
9
0
0
0
0
0
0
9
0
0
0
0
9
0
% H
% Ile:
0
0
9
0
0
0
0
9
0
0
0
0
9
0
0
% I
% Lys:
17
0
9
0
9
9
50
0
0
0
0
0
0
0
0
% K
% Leu:
0
50
50
0
0
9
0
9
9
0
9
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% M
% Asn:
0
0
0
0
17
0
9
0
0
0
0
9
0
9
0
% N
% Pro:
0
9
0
9
0
0
0
0
50
0
0
0
0
0
0
% P
% Gln:
50
9
0
0
0
0
0
0
9
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
0
25
0
9
0
59
0
0
0
9
9
0
0
% S
% Thr:
9
0
0
0
9
0
9
0
0
0
9
0
9
0
0
% T
% Val:
9
0
9
0
0
0
0
0
25
67
59
0
9
50
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
9
0
0
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _