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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HS3ST5
All Species:
30.3
Human Site:
Y170
Identified Species:
66.67
UniProt:
Q8IZT8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZT8
NP_705840.2
346
40408
Y170
E
E
V
P
E
R
I
Y
K
M
N
S
S
I
K
Chimpanzee
Pan troglodytes
XP_526526
307
35774
Y134
P
K
V
P
E
R
V
Y
S
M
N
P
S
I
R
Rhesus Macaque
Macaca mulatta
XP_001082139
346
40390
Y170
E
E
V
P
E
R
I
Y
K
M
N
S
S
I
K
Dog
Lupus familis
XP_539089
345
40397
Y169
E
E
V
P
E
R
I
Y
K
M
N
S
S
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSL4
346
40453
Y170
E
E
V
P
E
R
I
Y
K
M
N
S
S
I
K
Rat
Rattus norvegicus
Q9ESG5
311
35792
H138
P
K
V
P
E
R
I
H
S
M
N
P
T
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510276
345
40444
Y169
E
E
V
P
E
R
I
Y
K
M
N
S
S
I
K
Chicken
Gallus gallus
XP_426178
345
40454
Y169
E
E
V
P
E
R
I
Y
K
M
N
S
S
I
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074908
309
35901
H136
Q
V
A
P
A
R
I
H
A
M
N
S
S
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396407
369
42423
R172
P
E
V
P
E
R
I
R
A
M
N
A
S
V
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799088
345
40139
Y171
S
E
A
P
D
R
I
Y
R
M
N
S
S
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.1
99.4
97.9
N.A.
96.8
45.9
N.A.
92.4
93.6
N.A.
45.3
N.A.
N.A.
43.6
N.A.
43.3
Protein Similarity:
100
64.1
99.7
98.8
N.A.
97.6
62.7
N.A.
97.1
96.2
N.A.
60.9
N.A.
N.A.
60.1
N.A.
61.5
P-Site Identity:
100
60
100
100
N.A.
100
53.3
N.A.
100
100
N.A.
53.3
N.A.
N.A.
66.6
N.A.
73.3
P-Site Similarity:
100
80
100
100
N.A.
100
80
N.A.
100
100
N.A.
73.3
N.A.
N.A.
80
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
10
0
0
0
19
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
55
73
0
0
82
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
91
0
0
0
0
0
0
91
0
% I
% Lys:
0
19
0
0
0
0
0
0
55
0
0
0
0
0
73
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% N
% Pro:
28
0
0
100
0
0
0
0
0
0
0
19
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
100
0
10
10
0
0
0
0
0
28
% R
% Ser:
10
0
0
0
0
0
0
0
19
0
0
73
91
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
10
82
0
0
0
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _