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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DSEL All Species: 27.27
Human Site: T288 Identified Species: 85.71
UniProt: Q8IZU8 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZU8 NP_115536.1 1212 139238 T288 S Y T A K S V T Q Y V F L A Q
Chimpanzee Pan troglodytes XP_523962 1222 140274 T298 S Y T A K S V T Q Y V F L A Q
Rhesus Macaque Macaca mulatta XP_001098463 1185 135789 T298 S Y T A K S I T Q Y V F L A Q
Dog Lupus familis XP_541064 1212 139160 T288 S Y T A K S V T Q Y V F L A Q
Cat Felis silvestris
Mouse Mus musculus Q0VBN2 1207 138849 T283 S Y T S K S V T Q Y V F L A Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520171 1229 137870 T288 S Y T A K S I T Q Y V F L A Q
Chicken Gallus gallus XP_419114 1216 138974 T288 S Y T A K S I T Q Y V F L A Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787972 1183 135365 F295 Y H T V K P Q F Q R T L S V A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 95.7 94.7 N.A. 89.4 N.A. N.A. 76.2 77.8 N.A. N.A. N.A. N.A. N.A. N.A. 40.1
Protein Similarity: 100 99 96.2 97.7 N.A. 94.8 N.A. N.A. 84.8 88.7 N.A. N.A. N.A. N.A. N.A. N.A. 60.6
P-Site Identity: 100 100 93.3 100 N.A. 93.3 N.A. N.A. 93.3 93.3 N.A. N.A. N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 100 100 N.A. N.A. N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 75 0 0 0 0 0 0 0 0 0 88 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 13 0 0 0 88 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 38 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 13 88 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 13 0 100 0 0 0 0 0 88 % Q
% Arg: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % R
% Ser: 88 0 0 13 0 88 0 0 0 0 0 0 13 0 0 % S
% Thr: 0 0 100 0 0 0 0 88 0 0 13 0 0 0 0 % T
% Val: 0 0 0 13 0 0 50 0 0 0 88 0 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 88 0 0 0 0 0 0 0 88 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _