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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DSEL All Species: 22.73
Human Site: Y1028 Identified Species: 71.43
UniProt: Q8IZU8 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZU8 NP_115536.1 1212 139238 Y1028 G A S M R A L Y I V R D P R A
Chimpanzee Pan troglodytes XP_523962 1222 140274 Y1038 G A S M R A L Y I V R D P R A
Rhesus Macaque Macaca mulatta XP_001098463 1185 135789 Y1011 R D P R A W I Y S M L Y N S K
Dog Lupus familis XP_541064 1212 139160 Y1028 G A S M R A L Y I V R D P R A
Cat Felis silvestris
Mouse Mus musculus Q0VBN2 1207 138849 Y1023 G T S M R A L Y I V R D P R A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520171 1229 137870 Y1023 G P S L R A L Y V V R D P R A
Chicken Gallus gallus XP_419114 1216 138974 Y1032 G P S M R A L Y V V R D P R A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787972 1183 135365 H1005 K N T L H A I H F V R D P R A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 95.7 94.7 N.A. 89.4 N.A. N.A. 76.2 77.8 N.A. N.A. N.A. N.A. N.A. N.A. 40.1
Protein Similarity: 100 99 96.2 97.7 N.A. 94.8 N.A. N.A. 84.8 88.7 N.A. N.A. N.A. N.A. N.A. N.A. 60.6
P-Site Identity: 100 100 6.6 100 N.A. 93.3 N.A. N.A. 80 86.6 N.A. N.A. N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 100 20 100 N.A. 93.3 N.A. N.A. 93.3 93.3 N.A. N.A. N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 38 0 0 13 88 0 0 0 0 0 0 0 0 88 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 13 0 0 0 0 0 0 0 0 0 88 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % F
% Gly: 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 13 0 0 13 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 25 0 50 0 0 0 0 0 0 % I
% Lys: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % K
% Leu: 0 0 0 25 0 0 75 0 0 0 13 0 0 0 0 % L
% Met: 0 0 0 63 0 0 0 0 0 13 0 0 0 0 0 % M
% Asn: 0 13 0 0 0 0 0 0 0 0 0 0 13 0 0 % N
% Pro: 0 25 13 0 0 0 0 0 0 0 0 0 88 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 13 0 0 13 75 0 0 0 0 0 88 0 0 88 0 % R
% Ser: 0 0 75 0 0 0 0 0 13 0 0 0 0 13 0 % S
% Thr: 0 13 13 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 25 88 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 88 0 0 0 13 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _