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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA7
All Species:
27.88
Human Site:
S45
Identified Species:
55.76
UniProt:
Q8IZY2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZY2
NP_061985.2
2146
234350
S45
I
L
V
A
V
R
H
S
H
P
P
L
E
H
H
Chimpanzee
Pan troglodytes
XP_520163
2254
253166
S38
I
L
I
S
V
R
L
S
Y
P
P
Y
E
Q
H
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
S45
I
L
V
A
V
R
H
S
H
P
P
L
E
H
H
Dog
Lupus familis
XP_538773
2261
253895
S45
I
L
I
S
V
R
L
S
Y
P
P
Y
E
Q
H
Cat
Felis silvestris
Mouse
Mus musculus
Q91V24
2159
236865
S45
I
L
V
A
V
R
H
S
H
P
P
L
E
H
H
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
S45
I
L
V
A
V
R
H
S
H
P
P
L
E
H
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
N45
I
L
I
S
V
R
L
N
Y
P
P
Y
E
Q
H
Chicken
Gallus gallus
NP_989476
2260
254054
S45
I
L
I
S
V
R
L
S
Y
P
P
Y
E
Q
H
Frog
Xenopus laevis
NP_001089022
2363
267334
A45
I
L
V
W
L
R
N
A
N
P
L
Y
G
Q
H
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
Y45
I
L
I
S
V
R
L
Y
Y
P
P
Y
E
Q
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
L32
V
T
S
A
E
I
L
L
P
T
I
V
M
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51
95.3
51.2
N.A.
77.6
77.4
N.A.
51
51.6
43.2
51.1
N.A.
N.A.
N.A.
25.5
N.A.
Protein Similarity:
100
67.4
96.9
67.4
N.A.
85.2
84.9
N.A.
67.5
67.7
61
68.4
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
60
100
60
N.A.
100
100
N.A.
53.3
60
40
53.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
80
100
80
N.A.
100
100
N.A.
80
80
66.6
73.3
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
42
0
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
0
0
0
75
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
34
0
34
0
0
0
0
34
84
% H
% Ile:
84
0
42
0
0
9
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
84
0
0
9
0
50
9
0
0
9
34
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
9
9
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
84
75
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% Q
% Arg:
0
0
0
0
0
84
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
42
0
0
0
59
0
0
0
0
0
0
0
% S
% Thr:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
9
0
42
0
75
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
42
0
0
50
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _