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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA7 All Species: 7.58
Human Site: T788 Identified Species: 15.15
UniProt: Q8IZY2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZY2 NP_061985.2 2146 234350 T788 K S P A P C P T P L D P K V L
Chimpanzee Pan troglodytes XP_520163 2254 253166 S872 E K S H P G S S Q K R M S E I
Rhesus Macaque Macaca mulatta XP_001093459 2148 234326 T788 K S P A P C P T Q L D P K V L
Dog Lupus familis XP_538773 2261 253895 S879 E K S H P G S S Q K G V S E I
Cat Felis silvestris
Mouse Mus musculus Q91V24 2159 236865 A785 K S S V L A P A P Q D P K V L
Rat Rattus norvegicus Q7TNJ2 2170 237702 A786 K S S V L A P A P Q D P K V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516009 2266 254238 S884 V K S H P G S S R K G A S E I
Chicken Gallus gallus NP_989476 2260 254054 D880 D R Q H L H P D Q K G P S E V
Frog Xenopus laevis NP_001089022 2363 267334 V894 L V A D G D S V Q T E L S I H
Zebra Danio Brachydanio rerio NP_001139161 2268 254351 N883 W T T S V P S N R K E N A E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 A542 A D G A R D T A R A D I I V R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 M719 S G M D P Y S M R L T W Q L I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51 95.3 51.2 N.A. 77.6 77.4 N.A. 51 51.6 43.2 51.1 N.A. N.A. N.A. 25.5 N.A.
Protein Similarity: 100 67.4 96.9 67.4 N.A. 85.2 84.9 N.A. 67.5 67.7 61 68.4 N.A. N.A. N.A. 40.9 N.A.
P-Site Identity: 100 6.6 93.3 6.6 N.A. 60 60 N.A. 6.6 13.3 0 0 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 100 26.6 93.3 26.6 N.A. 60 60 N.A. 20 20 13.3 20 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 25 0 17 0 25 0 9 0 9 9 0 9 % A
% Cys: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 0 17 0 17 0 9 0 0 42 0 0 0 0 % D
% Glu: 17 0 0 0 0 0 0 0 0 0 17 0 0 42 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 9 0 9 25 0 0 0 0 25 0 0 0 0 % G
% His: 0 0 0 34 0 9 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 9 9 9 34 % I
% Lys: 34 25 0 0 0 0 0 0 0 42 0 0 34 0 0 % K
% Leu: 9 0 0 0 25 0 0 0 0 25 0 9 0 9 34 % L
% Met: 0 0 9 0 0 0 0 9 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 0 % N
% Pro: 0 0 17 0 50 9 42 0 25 0 0 42 0 0 0 % P
% Gln: 0 0 9 0 0 0 0 0 42 17 0 0 9 0 0 % Q
% Arg: 0 9 0 0 9 0 0 0 34 0 9 0 0 0 9 % R
% Ser: 9 34 42 9 0 0 50 25 0 0 0 0 42 0 0 % S
% Thr: 0 9 9 0 0 0 9 17 0 9 9 0 0 0 0 % T
% Val: 9 9 0 17 9 0 0 9 0 0 0 9 0 42 9 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _