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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CENPL All Species: 23.03
Human Site: S310 Identified Species: 46.06
UniProt: Q8N0S6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N0S6 NP_001120653.1 344 38998 S310 R L V R V S T S V A S A H T D
Chimpanzee Pan troglodytes XP_001150411 344 38954 S310 R L V R V S T S V A S A H T D
Rhesus Macaque Macaca mulatta XP_001102194 344 39061 S310 R L V R V S T S V A S A H T D
Dog Lupus familis XP_853950 435 49420 S385 R L V R V S T S V A S A H T D
Cat Felis silvestris
Mouse Mus musculus Q3U3S3 329 37679 F296 Y S H F H R H F K I H L A A T
Rat Rattus norvegicus Q3ZAU7 345 39442 S311 R L V R V S T S V A S A H T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515206 339 38259 A305 R L V R V S T A I A S A H T D
Chicken Gallus gallus Q1T7C0 344 37874 G310 K L V K V S T G I A S A H C D
Frog Xenopus laevis NP_001090496 348 38724 S313 H L V K V S T S V A S A H C D
Zebra Danio Brachydanio rerio Q6DRD4 367 40618 S330 A G T L L K V S T A L G S A H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793614 365 40499 A327 Y L K T I G T A A A F V G A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SS37 247 27894 M214 E D E V D G F M D S M I M K F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 95.9 68.9 N.A. 78.7 84.3 N.A. 68.3 58.7 56 37.8 N.A. N.A. N.A. N.A. 30.1
Protein Similarity: 100 99.1 98.8 73.3 N.A. 87.2 92.1 N.A. 80.5 72 70.9 57.2 N.A. N.A. N.A. N.A. 43.2
P-Site Identity: 100 100 100 100 N.A. 0 100 N.A. 86.6 66.6 80 13.3 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 0 100 N.A. 100 86.6 86.6 20 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. 20.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 34.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 17 9 84 0 67 9 25 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % C
% Asp: 0 9 0 0 9 0 0 0 9 0 0 0 0 0 67 % D
% Glu: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % E
% Phe: 0 0 0 9 0 0 9 9 0 0 9 0 0 0 9 % F
% Gly: 0 9 0 0 0 17 0 9 0 0 0 9 9 0 0 % G
% His: 9 0 9 0 9 0 9 0 0 0 9 0 67 0 9 % H
% Ile: 0 0 0 0 9 0 0 0 17 9 0 9 0 0 0 % I
% Lys: 9 0 9 17 0 9 0 0 9 0 0 0 0 9 0 % K
% Leu: 0 75 0 9 9 0 0 0 0 0 9 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 9 0 0 9 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 50 0 0 50 0 9 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 0 0 0 67 0 59 0 9 67 0 9 0 0 % S
% Thr: 0 0 9 9 0 0 75 0 9 0 0 0 0 50 9 % T
% Val: 0 0 67 9 67 0 9 0 50 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _