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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM185A
All Species:
14.55
Human Site:
S181
Identified Species:
35.56
UniProt:
Q8N0U4
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N0U4
NP_001138740.1
392
42301
S181
I
E
T
E
H
G
T
S
I
L
Q
S
V
K
G
Chimpanzee
Pan troglodytes
XP_001157204
392
42284
S181
I
E
T
E
H
G
T
S
I
L
Q
S
V
K
G
Rhesus Macaque
Macaca mulatta
XP_001084177
392
42246
S181
I
E
T
E
H
G
T
S
V
L
Q
S
V
K
G
Dog
Lupus familis
XP_533108
184
20008
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPD2
378
39974
S167
I
D
T
E
Q
G
T
S
I
L
Q
S
V
K
S
Rat
Rattus norvegicus
NP_001121660
208
21749
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507663
396
41290
T152
S
S
V
S
G
N
I
T
L
G
S
I
H
G
K
Chicken
Gallus gallus
XP_415967
309
33724
S101
K
G
T
S
V
L
Q
S
I
K
S
H
K
I
D
Frog
Xenopus laevis
NP_001090051
249
27335
P41
A
A
E
P
R
N
K
P
L
K
Q
W
T
L
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93W77
231
24750
R23
L
V
K
S
S
S
T
R
N
G
F
P
V
I
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
93.1
38.7
N.A.
70.6
36.7
N.A.
25.2
46.9
30.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
94.9
43.6
N.A.
78.5
41.5
N.A.
40.1
60.7
42
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
80
0
N.A.
0
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
0
N.A.
86.6
0
N.A.
13.3
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
30
10
40
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
10
0
0
10
40
0
0
0
20
0
0
0
10
30
% G
% His:
0
0
0
0
30
0
0
0
0
0
0
10
10
0
0
% H
% Ile:
40
0
0
0
0
0
10
0
40
0
0
10
0
20
10
% I
% Lys:
10
0
10
0
0
0
10
0
0
20
0
0
10
40
10
% K
% Leu:
10
0
0
0
0
10
0
0
20
40
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
20
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
10
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
10
0
10
0
0
0
50
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
30
10
10
0
50
0
0
20
40
0
0
20
% S
% Thr:
0
0
50
0
0
0
50
10
0
0
0
0
10
0
0
% T
% Val:
0
10
10
0
10
0
0
0
10
0
0
0
50
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _