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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VKORC1L1
All Species:
21.82
Human Site:
S64
Identified Species:
53.33
UniProt:
Q8N0U8
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N0U8
NP_775788.2
176
19836
S64
K
C
S
A
A
L
A
S
R
W
G
R
G
F
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088069
176
19803
S64
K
C
S
A
A
L
A
S
R
W
G
R
G
F
G
Dog
Lupus familis
XP_848485
176
19785
S64
K
C
S
A
A
L
A
S
R
W
G
R
G
F
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CRC0
161
17750
S56
I
S
C
S
R
V
F
S
S
R
W
G
R
G
F
Rat
Rattus norvegicus
Q6TEK3
176
19760
S64
K
C
S
A
A
L
A
S
R
W
G
R
G
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519067
74
8486
Chicken
Gallus gallus
NP_001001328
176
19747
S64
R
C
S
A
A
I
T
S
R
W
G
R
G
F
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
NP_001027940
175
19564
S63
S
C
S
K
V
F
G
S
R
W
G
R
G
F
G
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120000
169
19068
K62
S
E
H
V
S
C
T
K
A
F
F
S
E
Y
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181369
160
17984
K52
V
F
T
S
K
Y
G
K
G
F
G
I
I
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.4
97.7
N.A.
46
97.1
N.A.
38
83.5
N.A.
N.A.
72.1
N.A.
34
N.A.
42.6
Protein Similarity:
100
N.A.
100
100
N.A.
65.3
99.4
N.A.
40.3
92.6
N.A.
N.A.
83.5
N.A.
54.5
N.A.
61.9
P-Site Identity:
100
N.A.
100
100
N.A.
6.6
100
N.A.
0
80
N.A.
N.A.
66.6
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
20
100
N.A.
0
93.3
N.A.
N.A.
66.6
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
50
50
0
40
0
10
0
0
0
0
0
0
% A
% Cys:
0
60
10
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
10
0
0
0
10
10
0
0
20
10
0
0
60
10
% F
% Gly:
0
0
0
0
0
0
20
0
10
0
70
10
60
20
70
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
0
0
0
0
10
10
0
0
% I
% Lys:
40
0
0
10
10
0
0
20
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
40
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
0
0
0
10
0
0
0
60
10
0
60
10
0
0
% R
% Ser:
20
10
60
20
10
0
0
70
10
0
0
10
0
0
0
% S
% Thr:
0
0
10
0
0
0
20
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
10
10
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
60
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _