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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VKORC1L1 All Species: 21.82
Human Site: S64 Identified Species: 53.33
UniProt: Q8N0U8 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N0U8 NP_775788.2 176 19836 S64 K C S A A L A S R W G R G F G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088069 176 19803 S64 K C S A A L A S R W G R G F G
Dog Lupus familis XP_848485 176 19785 S64 K C S A A L A S R W G R G F G
Cat Felis silvestris
Mouse Mus musculus Q9CRC0 161 17750 S56 I S C S R V F S S R W G R G F
Rat Rattus norvegicus Q6TEK3 176 19760 S64 K C S A A L A S R W G R G F G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519067 74 8486
Chicken Gallus gallus NP_001001328 176 19747 S64 R C S A A I T S R W G R G F G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres NP_001027940 175 19564 S63 S C S K V F G S R W G R G F G
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120000 169 19068 K62 S E H V S C T K A F F S E Y G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181369 160 17984 K52 V F T S K Y G K G F G I I G Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.4 97.7 N.A. 46 97.1 N.A. 38 83.5 N.A. N.A. 72.1 N.A. 34 N.A. 42.6
Protein Similarity: 100 N.A. 100 100 N.A. 65.3 99.4 N.A. 40.3 92.6 N.A. N.A. 83.5 N.A. 54.5 N.A. 61.9
P-Site Identity: 100 N.A. 100 100 N.A. 6.6 100 N.A. 0 80 N.A. N.A. 66.6 N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 20 100 N.A. 0 93.3 N.A. N.A. 66.6 N.A. 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 50 50 0 40 0 10 0 0 0 0 0 0 % A
% Cys: 0 60 10 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % E
% Phe: 0 10 0 0 0 10 10 0 0 20 10 0 0 60 10 % F
% Gly: 0 0 0 0 0 0 20 0 10 0 70 10 60 20 70 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 10 0 0 0 0 0 10 10 0 0 % I
% Lys: 40 0 0 10 10 0 0 20 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 40 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 10 0 0 0 10 0 0 0 60 10 0 60 10 0 0 % R
% Ser: 20 10 60 20 10 0 0 70 10 0 0 10 0 0 0 % S
% Thr: 0 0 10 0 0 0 20 0 0 0 0 0 0 0 0 % T
% Val: 10 0 0 10 10 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 60 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _