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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VKORC1L1
All Species:
22.73
Human Site:
Y162
Identified Species:
55.56
UniProt:
Q8N0U8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N0U8
NP_775788.2
176
19836
Y162
I
N
Y
K
R
L
V
Y
L
N
E
A
W
K
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088069
176
19803
Y162
I
N
Y
K
R
L
V
Y
L
N
E
A
W
K
R
Dog
Lupus familis
XP_848485
176
19785
Y162
I
N
Y
K
R
L
V
Y
L
N
E
A
W
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CRC0
161
17750
P154
L
L
S
F
Q
K
V
P
E
H
K
T
K
K
H
Rat
Rattus norvegicus
Q6TEK3
176
19760
Y162
I
N
Y
K
R
L
V
Y
L
N
E
A
W
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519067
74
8486
R67
Y
L
N
E
A
W
K
R
H
L
Q
P
K
Q
D
Chicken
Gallus gallus
NP_001001328
176
19747
Y162
I
N
Y
K
R
L
V
Y
L
N
E
A
W
K
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
NP_001027940
175
19564
Y161
L
N
Y
K
R
L
V
Y
L
N
E
A
W
K
Q
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120000
169
19068
L160
A
I
K
K
H
R
R
L
F
R
N
R
Q
I
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181369
160
17984
E150
R
W
N
S
E
R
R
E
R
K
Y
T
R
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.4
97.7
N.A.
46
97.1
N.A.
38
83.5
N.A.
N.A.
72.1
N.A.
34
N.A.
42.6
Protein Similarity:
100
N.A.
100
100
N.A.
65.3
99.4
N.A.
40.3
92.6
N.A.
N.A.
83.5
N.A.
54.5
N.A.
61.9
P-Site Identity:
100
N.A.
100
100
N.A.
13.3
100
N.A.
0
100
N.A.
N.A.
86.6
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
40
100
N.A.
20
100
N.A.
N.A.
100
N.A.
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
0
0
0
60
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
10
10
0
0
10
10
0
60
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
10
10
0
0
0
0
10
% H
% Ile:
50
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
10
70
0
10
10
0
0
10
10
0
20
80
10
% K
% Leu:
20
20
0
0
0
60
0
10
60
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
60
20
0
0
0
0
0
0
60
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
10
0
10
10
10
% Q
% Arg:
10
0
0
0
60
20
20
10
10
10
0
10
10
0
50
% R
% Ser:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% T
% Val:
0
0
0
0
0
0
70
0
0
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
10
0
0
0
0
0
0
60
0
0
% W
% Tyr:
10
0
60
0
0
0
0
60
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _