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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LGI2
All Species:
20.3
Human Site:
Y200
Identified Species:
49.63
UniProt:
Q8N0V4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N0V4
NP_060646.2
545
62298
Y200
L
C
I
G
P
P
E
Y
Q
E
K
K
L
N
D
Chimpanzee
Pan troglodytes
Q1EGL2
557
63773
Y206
Y
C
E
G
P
P
E
Y
K
K
R
K
I
N
S
Rhesus Macaque
Macaca mulatta
XP_001082016
545
62217
Y200
L
C
S
G
P
P
E
Y
Q
E
K
K
L
N
D
Dog
Lupus familis
XP_545971
529
60789
Y184
L
C
I
G
P
P
E
Y
Q
E
K
K
L
N
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4Z0
550
62988
L205
A
K
Q
R
G
W
Q
L
E
L
S
L
G
F
C
Rat
Rattus norvegicus
Q8K4Y5
557
63709
Y206
Y
C
E
G
P
P
E
Y
K
K
R
K
I
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513725
484
55978
D158
D
Y
E
C
T
T
T
D
F
V
V
H
Q
I
L
Chicken
Gallus gallus
XP_001232758
575
64997
Y230
L
C
I
G
P
A
E
Y
Q
D
K
K
L
N
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001034730
536
61103
M191
L
C
A
G
P
E
E
M
K
G
K
R
L
N
D
Tiger Blowfish
Takifugu rubipres
NP_001072089
536
60739
M192
A
C
A
G
P
E
D
M
K
G
K
S
L
N
D
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.1
99.4
93.7
N.A.
84.9
54.9
N.A.
84
83.1
N.A.
70.2
68.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
71.4
99.4
94.8
N.A.
88.5
71.4
N.A.
87.7
88.5
N.A.
86
83.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
93.3
100
N.A.
0
53.3
N.A.
0
86.6
N.A.
60
46.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
93.3
100
N.A.
13.3
80
N.A.
0
93.3
N.A.
73.3
60
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
20
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
80
0
10
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
0
0
0
0
0
10
10
0
10
0
0
0
0
60
% D
% Glu:
0
0
30
0
0
20
70
0
10
30
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% F
% Gly:
0
0
0
80
10
0
0
0
0
20
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
30
0
0
0
0
0
0
0
0
0
20
10
0
% I
% Lys:
0
10
0
0
0
0
0
0
40
20
60
60
0
0
0
% K
% Leu:
50
0
0
0
0
0
0
10
0
10
0
10
60
0
10
% L
% Met:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
0
% N
% Pro:
0
0
0
0
80
50
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
10
0
40
0
0
0
10
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
20
10
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
0
0
0
10
10
0
0
20
% S
% Thr:
0
0
0
0
10
10
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
20
10
0
0
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _