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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FUK
All Species:
9.09
Human Site:
S545
Identified Species:
20
UniProt:
Q8N0W3
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N0W3
NP_659496.2
1084
117623
S545
D
R
A
A
T
L
A
S
R
R
D
L
F
F
R
Chimpanzee
Pan troglodytes
XP_001170471
1084
117569
S545
D
R
A
A
T
L
A
S
R
R
D
L
F
F
R
Rhesus Macaque
Macaca mulatta
XP_001107211
1084
117771
S545
D
R
A
A
T
L
A
S
R
R
D
L
F
F
R
Dog
Lupus familis
XP_546835
1079
117343
F545
D
R
A
A
T
L
A
F
R
R
D
L
F
F
R
Cat
Felis silvestris
Mouse
Mus musculus
NP_758487
1090
119249
F545
D
R
A
A
T
L
D
F
R
R
D
L
F
F
C
Rat
Rattus norvegicus
NP_001100899
1019
111165
F545
D
R
A
A
T
L
D
F
R
R
D
L
F
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506585
853
91812
Q412
Y
S
Q
V
E
E
P
Q
L
L
E
D
G
C
S
Chicken
Gallus gallus
XP_001233364
541
57981
G100
G
E
G
G
L
R
S
G
P
A
A
N
R
E
W
Frog
Xenopus laevis
NP_001108290
1086
119092
N551
D
Q
E
K
A
L
Q
N
R
R
Q
T
F
F
R
Zebra Danio
Brachydanio rerio
XP_001344272
979
105900
L533
S
L
R
D
I
L
I
L
T
D
Q
Q
T
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_495756
839
94445
G398
I
A
S
D
G
K
G
G
L
R
N
G
P
A
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.1
89.4
N.A.
85.1
79.6
N.A.
38
35.1
58.7
48.4
N.A.
N.A.
N.A.
24.1
N.A.
Protein Similarity:
100
99.6
98.5
93.1
N.A.
90.7
84.9
N.A.
48.5
40.9
73.5
61.7
N.A.
N.A.
N.A.
41.1
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
86.6
N.A.
0
0
46.6
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
80
86.6
N.A.
6.6
6.6
60
6.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
55
55
10
0
37
0
0
10
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% C
% Asp:
64
0
0
19
0
0
19
0
0
10
55
10
0
0
0
% D
% Glu:
0
10
10
0
10
10
0
0
0
0
10
0
0
19
0
% E
% Phe:
0
0
0
0
0
0
0
28
0
0
0
0
64
64
0
% F
% Gly:
10
0
10
10
10
0
10
19
0
0
0
10
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
10
0
0
10
73
0
10
19
10
0
55
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
10
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
10
0
0
0
10
0
0
% P
% Gln:
0
10
10
0
0
0
10
10
0
0
19
10
0
0
0
% Q
% Arg:
0
55
10
0
0
10
0
0
64
73
0
0
10
0
55
% R
% Ser:
10
10
10
0
0
0
10
28
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
55
0
0
0
10
0
0
10
10
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _