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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IQCK All Species: 8.48
Human Site: T111 Identified Species: 26.67
UniProt: Q8N0W5 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N0W5 NP_694940.1 287 33292 T111 H F T M I S R T P C P Q D K S
Chimpanzee Pan troglodytes XP_510861 287 33331 T111 H F T M I S H T P C P Q D K S
Rhesus Macaque Macaca mulatta XP_001084890 287 33297 T111 H F T M I S H T P C P Q D K S
Dog Lupus familis XP_536951 285 32959 V113 H L T M D S H V P C P Q V Q L
Cat Felis silvestris
Mouse Mus musculus NP_001074915 287 32963 V113 Q F P A M P P V P C P P K K A
Rat Rattus norvegicus XP_001078905 286 32671 V116 Q F P V T P P V P C P P K K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_424597 304 34459 I140 V V Q Q L L P I P E A P P L P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780827 337 38735 N158 T E Y L W R H N P S V T G R E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 94.4 72.1 N.A. 72.4 67.2 N.A. N.A. 45 N.A. N.A. N.A. N.A. N.A. N.A. 29.6
Protein Similarity: 100 98.6 95.8 80.1 N.A. 81.8 77.3 N.A. N.A. 58.5 N.A. N.A. N.A. N.A. N.A. N.A. 44.8
P-Site Identity: 100 93.3 93.3 53.3 N.A. 33.3 33.3 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 93.3 93.3 60 N.A. 46.6 46.6 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 13 0 0 0 0 0 0 13 0 0 0 25 % A
% Cys: 0 0 0 0 0 0 0 0 0 75 0 0 0 0 0 % C
% Asp: 0 0 0 0 13 0 0 0 0 0 0 0 38 0 0 % D
% Glu: 0 13 0 0 0 0 0 0 0 13 0 0 0 0 13 % E
% Phe: 0 63 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % G
% His: 50 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 38 0 0 13 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 25 63 0 % K
% Leu: 0 13 0 13 13 13 0 0 0 0 0 0 0 13 13 % L
% Met: 0 0 0 50 13 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % N
% Pro: 0 0 25 0 0 25 38 0 100 0 75 38 13 0 13 % P
% Gln: 25 0 13 13 0 0 0 0 0 0 0 50 0 13 0 % Q
% Arg: 0 0 0 0 0 13 13 0 0 0 0 0 0 13 0 % R
% Ser: 0 0 0 0 0 50 0 0 0 13 0 0 0 0 38 % S
% Thr: 13 0 50 0 13 0 0 38 0 0 0 13 0 0 0 % T
% Val: 13 13 0 13 0 0 0 38 0 0 13 0 13 0 0 % V
% Trp: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _