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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC5 All Species: 20
Human Site: S295 Identified Species: 40
UniProt: Q8N0Z6 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N0Z6 NP_612385.2 440 48928 S295 K L Q S M L G S L R P A H L G
Chimpanzee Pan troglodytes XP_520664 440 48965 S295 K L Q S M L G S L R P A H L G
Rhesus Macaque Macaca mulatta XP_001091691 320 36000 S181 M D V H D G R S W Y I L G N S
Dog Lupus familis XP_853663 486 53619 S341 K L Q S M L G S L R P A H L G
Cat Felis silvestris
Mouse Mus musculus Q99LG4 440 48779 S295 K L Q S M L G S L R P A H L G
Rat Rattus norvegicus Q5BK48 440 48775 N295 K L Q S M L G N L R P A H L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515437 114 12297
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001017654 446 49645 S301 R L R N M L S S L S T S A L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394646 430 49125 K287 V N N S G R V K P K R L Y Q M
Nematode Worm Caenorhab. elegans NP_490922 402 45164 F260 T R E K L A S F V S Y L S K F
Sea Urchin Strong. purpuratus XP_784804 627 69496 S295 R L Q Q L M S S F K Q N D L G
Poplar Tree Populus trichocarpa XP_002314823 392 43949 F253 Y E R A L S G F E A A A L K D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 71.8 81.4 N.A. 90.4 90.2 N.A. 21.1 N.A. N.A. 57.6 N.A. N.A. 46.5 23.4 37
Protein Similarity: 100 100 72.5 87 N.A. 94.7 95 N.A. 23.8 N.A. N.A. 74.4 N.A. N.A. 63.4 45.9 50.4
P-Site Identity: 100 100 6.6 100 N.A. 100 93.3 N.A. 0 N.A. N.A. 46.6 N.A. N.A. 6.6 0 33.3
P-Site Similarity: 100 100 6.6 100 N.A. 100 100 N.A. 0 N.A. N.A. 73.3 N.A. N.A. 20 20 60
Percent
Protein Identity: 30.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 47.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 9 0 0 0 9 9 50 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 9 0 0 0 0 0 0 0 9 0 9 % D
% Glu: 0 9 9 0 0 0 0 0 9 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 17 9 0 0 0 0 0 9 % F
% Gly: 0 0 0 0 9 9 50 0 0 0 0 0 9 0 59 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 42 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % I
% Lys: 42 0 0 9 0 0 0 9 0 17 0 0 0 17 0 % K
% Leu: 0 59 0 0 25 50 0 0 50 0 0 25 9 59 0 % L
% Met: 9 0 0 0 50 9 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 9 9 9 0 0 0 9 0 0 0 9 0 9 0 % N
% Pro: 0 0 0 0 0 0 0 0 9 0 42 0 0 0 0 % P
% Gln: 0 0 50 9 0 0 0 0 0 0 9 0 0 9 0 % Q
% Arg: 17 9 17 0 0 9 9 0 0 42 9 0 0 0 0 % R
% Ser: 0 0 0 50 0 9 25 59 0 17 0 9 9 0 9 % S
% Thr: 9 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % T
% Val: 9 0 9 0 0 0 9 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 9 9 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _