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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC5 All Species: 25.45
Human Site: S85 Identified Species: 50.91
UniProt: Q8N0Z6 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N0Z6 NP_612385.2 440 48928 S85 L N V T P D Y S P K A E E L L
Chimpanzee Pan troglodytes XP_520664 440 48965 S85 L N V T P D Y S P K A E E L L
Rhesus Macaque Macaca mulatta XP_001091691 320 36000
Dog Lupus familis XP_853663 486 53619 S131 L N V T P D Y S P K A E E L L
Cat Felis silvestris
Mouse Mus musculus Q99LG4 440 48779 S85 L N V T P D Y S P E A E V L L
Rat Rattus norvegicus Q5BK48 440 48775 S85 L N V T P D Y S P E A E V L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515437 114 12297
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001017654 446 49645 S90 L N V A P E F S Q A A E E C L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394646 430 49125 I88 L N V T E R F I P Q A E E L L
Nematode Worm Caenorhab. elegans NP_490922 402 45164 K67 L L L A E G G K M Y N V L E D
Sea Urchin Strong. purpuratus XP_784804 627 69496 S87 W N I L P S F S P E A L G A L
Poplar Tree Populus trichocarpa XP_002314823 392 43949 S62 I S K L Q S Q S D L S L N L L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 71.8 81.4 N.A. 90.4 90.2 N.A. 21.1 N.A. N.A. 57.6 N.A. N.A. 46.5 23.4 37
Protein Similarity: 100 100 72.5 87 N.A. 94.7 95 N.A. 23.8 N.A. N.A. 74.4 N.A. N.A. 63.4 45.9 50.4
P-Site Identity: 100 100 0 100 N.A. 86.6 86.6 N.A. 0 N.A. N.A. 60 N.A. N.A. 66.6 6.6 40
P-Site Similarity: 100 100 0 100 N.A. 93.3 93.3 N.A. 0 N.A. N.A. 73.3 N.A. N.A. 80 13.3 60
Percent
Protein Identity: 30.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 47.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 40 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 17 0 0 0 0 0 9 67 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 0 0 0 42 0 0 9 0 0 0 0 0 9 % D
% Glu: 0 0 0 0 17 9 0 0 0 25 0 59 42 9 0 % E
% Phe: 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 9 0 0 0 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % I
% Lys: 0 0 9 0 0 0 0 9 0 25 0 0 0 0 0 % K
% Leu: 67 9 9 17 0 0 0 0 0 9 0 17 9 59 75 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 67 0 0 0 0 0 0 0 0 9 0 9 0 0 % N
% Pro: 0 0 0 0 59 0 0 0 59 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 9 0 9 0 9 9 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 0 0 0 17 0 67 0 0 9 0 0 0 0 % S
% Thr: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 59 0 0 0 0 0 0 0 0 9 17 0 0 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 42 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _