KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC5
All Species:
17.27
Human Site:
Y403
Identified Species:
34.55
UniProt:
Q8N0Z6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N0Z6
NP_612385.2
440
48928
Y403
I
Q
H
K
G
K
D
Y
S
F
S
S
V
R
V
Chimpanzee
Pan troglodytes
XP_520664
440
48965
Y403
I
Q
H
R
G
K
D
Y
S
F
S
S
V
R
V
Rhesus Macaque
Macaca mulatta
XP_001091691
320
36000
S284
L
L
E
S
K
D
Y
S
F
S
S
V
R
V
E
Dog
Lupus familis
XP_853663
486
53619
F449
I
Q
H
K
G
K
D
F
S
F
A
S
V
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99LG4
440
48779
Y403
I
R
H
K
G
K
D
Y
S
F
S
S
V
R
V
Rat
Rattus norvegicus
Q5BK48
440
48775
Y403
I
Q
H
K
G
K
D
Y
S
F
S
S
V
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515437
114
12297
K78
Y
Q
A
A
S
G
Q
K
M
T
L
E
R
K
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001017654
446
49645
Y409
V
T
H
K
D
K
S
Y
D
F
R
S
I
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394646
430
49125
F393
A
I
P
E
P
F
D
F
D
F
K
S
I
R
V
Nematode Worm
Caenorhab. elegans
NP_490922
402
45164
H365
I
P
S
D
P
E
I
H
V
D
S
V
K
W
I
Sea Urchin
Strong. purpuratus
XP_784804
627
69496
I590
F
T
V
D
N
K
H
I
Q
F
S
S
L
R
V
Poplar Tree
Populus trichocarpa
XP_002314823
392
43949
L356
S
N
Q
I
C
F
V
L
S
V
Y
G
M
R
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
71.8
81.4
N.A.
90.4
90.2
N.A.
21.1
N.A.
N.A.
57.6
N.A.
N.A.
46.5
23.4
37
Protein Similarity:
100
100
72.5
87
N.A.
94.7
95
N.A.
23.8
N.A.
N.A.
74.4
N.A.
N.A.
63.4
45.9
50.4
P-Site Identity:
100
93.3
6.6
86.6
N.A.
93.3
100
N.A.
6.6
N.A.
N.A.
53.3
N.A.
N.A.
33.3
13.3
40
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
13.3
N.A.
N.A.
66.6
N.A.
N.A.
53.3
33.3
46.6
Percent
Protein Identity:
30.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
47.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
9
0
0
0
0
0
0
9
0
0
0
9
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
9
9
50
0
17
9
0
0
0
0
0
% D
% Glu:
0
0
9
9
0
9
0
0
0
0
0
9
0
0
9
% E
% Phe:
9
0
0
0
0
17
0
17
9
67
0
0
0
0
0
% F
% Gly:
0
0
0
0
42
9
0
0
0
0
0
9
0
0
0
% G
% His:
0
0
50
0
0
0
9
9
0
0
0
0
0
0
0
% H
% Ile:
50
9
0
9
0
0
9
9
0
0
0
0
17
0
9
% I
% Lys:
0
0
0
42
9
59
0
9
0
0
9
0
9
9
0
% K
% Leu:
9
9
0
0
0
0
0
9
0
0
9
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% M
% Asn:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
9
9
0
17
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
42
9
0
0
0
9
0
9
0
0
0
0
0
0
% Q
% Arg:
0
9
0
9
0
0
0
0
0
0
9
0
17
75
0
% R
% Ser:
9
0
9
9
9
0
9
9
50
9
59
67
0
0
0
% S
% Thr:
0
17
0
0
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
9
0
9
0
0
0
9
0
9
9
0
17
42
9
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
9
0
0
0
0
0
9
42
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _