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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PUSL1
All Species:
4.85
Human Site:
S291
Identified Species:
8.21
UniProt:
Q8N0Z8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N0Z8
NP_699170.1
303
33233
S291
Y
G
N
L
G
A
A
S
C
T
L
Q
G
P
Q
Chimpanzee
Pan troglodytes
XP_513709
293
32103
K282
L
L
F
R
F
Y
W
K
L
L
S
R
T
T
C
Rhesus Macaque
Macaca mulatta
XP_001093509
505
54336
S493
Y
G
S
L
G
A
A
S
C
T
L
Q
G
P
Q
Dog
Lupus familis
XP_546716
294
32482
N283
L
K
S
V
L
Y
E
N
L
G
E
E
L
L
V
Cat
Felis silvestris
Mouse
Mus musculus
A2ADA5
291
31974
L279
A
P
A
R
G
L
F
L
K
S
V
L
Y
D
N
Rat
Rattus norvegicus
NP_001102169
127
14145
K116
P
A
H
G
L
F
L
K
S
V
L
Y
D
N
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417580
291
32818
N280
F
L
K
S
V
E
Y
N
E
A
D
L
Q
T
V
Frog
Xenopus laevis
Q6GQ53
298
33665
G284
Y
D
G
T
E
L
N
G
F
S
A
E
E
T
Q
Zebra Danio
Brachydanio rerio
XP_683563
290
32910
Y277
L
F
L
T
N
V
Q
Y
R
D
T
D
L
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036574
306
35200
Y295
L
A
P
A
C
G
L
Y
L
C
R
V
H
Y
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781664
306
35062
H289
Y
Y
A
M
S
R
L
H
L
L
K
T
H
P
L
Poplar Tree
Populus trichocarpa
XP_002331109
326
36158
D289
L
K
S
V
G
T
G
D
L
T
V
S
D
V
E
Maize
Zea mays
NP_001146958
386
42294
A365
L
D
A
K
T
V
T
A
A
P
S
M
A
P
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172451
372
41526
P358
S
A
A
K
P
M
A
P
A
S
G
L
Y
L
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.9
46.7
78.8
N.A.
76.9
35.3
N.A.
N.A.
50.1
50.1
46.2
N.A.
30.3
N.A.
N.A.
42.8
Protein Similarity:
100
74.9
52.4
83.1
N.A.
83.8
36.6
N.A.
N.A.
64.3
66.6
62.3
N.A.
50.9
N.A.
N.A.
60.4
P-Site Identity:
100
0
93.3
0
N.A.
6.6
6.6
N.A.
N.A.
0
13.3
0
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
6.6
100
26.6
N.A.
20
13.3
N.A.
N.A.
13.3
26.6
0
N.A.
6.6
N.A.
N.A.
20
Percent
Protein Identity:
33.4
28.7
N.A.
27.9
N.A.
N.A.
Protein Similarity:
50.3
41.7
N.A.
44.8
N.A.
N.A.
P-Site Identity:
13.3
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
40
13.3
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
22
29
8
0
15
22
8
15
8
8
0
8
0
15
% A
% Cys:
0
0
0
0
8
0
0
0
15
8
0
0
0
0
8
% C
% Asp:
0
15
0
0
0
0
0
8
0
8
8
8
15
8
0
% D
% Glu:
0
0
0
0
8
8
8
0
8
0
8
15
8
0
8
% E
% Phe:
8
8
8
0
8
8
8
0
8
0
0
0
0
0
8
% F
% Gly:
0
15
8
8
29
8
8
8
0
8
8
0
15
0
0
% G
% His:
0
0
8
0
0
0
0
8
0
0
0
0
15
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
15
8
15
0
0
0
15
8
0
8
0
0
0
0
% K
% Leu:
43
15
8
15
15
15
22
8
36
15
22
22
15
15
8
% L
% Met:
0
0
0
8
0
8
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
8
0
8
15
0
0
0
0
0
8
8
% N
% Pro:
8
8
8
0
8
0
0
8
0
8
0
0
0
29
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
15
8
0
22
% Q
% Arg:
0
0
0
15
0
8
0
0
8
0
8
8
0
0
8
% R
% Ser:
8
0
22
8
8
0
0
15
8
22
15
8
0
0
8
% S
% Thr:
0
0
0
15
8
8
8
0
0
22
8
8
8
22
0
% T
% Val:
0
0
0
15
8
15
0
0
0
8
15
8
0
15
15
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
29
8
0
0
0
15
8
15
0
0
0
8
15
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _