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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHISA5
All Species:
9.09
Human Site:
Y221
Identified Species:
22.22
UniProt:
Q8N114
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N114
NP_057563.3
240
25582
Y221
A
G
G
A
A
A
P
Y
P
A
S
Q
P
P
Y
Chimpanzee
Pan troglodytes
XP_516437
240
25611
Y221
A
G
G
A
A
A
P
Y
P
A
S
Q
P
P
Y
Rhesus Macaque
Macaca mulatta
XP_001098155
238
25265
Y219
A
G
G
A
A
A
P
Y
P
A
S
Q
P
P
Y
Dog
Lupus familis
XP_851338
160
17059
P142
G
G
A
A
M
P
Y
P
A
S
Q
P
P
Y
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7I0
235
25499
G217
P
Y
H
E
S
L
A
G
A
S
Q
P
P
Y
N
Rat
Rattus norvegicus
Q5XIH2
130
13863
G112
A
Y
H
E
T
L
A
G
A
S
Q
P
P
Y
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509212
245
26727
A220
A
Y
H
E
T
V
A
A
G
A
G
A
P
Y
P
Chicken
Gallus gallus
Q5ZIS9
139
14829
P121
A
G
A
G
A
P
Y
P
I
S
Q
P
P
Y
N
Frog
Xenopus laevis
NP_001089674
218
24416
N200
P
T
A
P
Q
P
Y
N
P
N
G
P
P
P
Y
Zebra Danio
Brachydanio rerio
NP_001038335
261
27870
Q220
P
A
Q
P
G
Y
G
Q
P
G
Y
G
Q
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
93.7
56.2
N.A.
65.8
42.9
N.A.
54.2
42.9
28.7
24.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
95.4
60
N.A.
74.1
47
N.A.
63.6
46.6
40.8
33.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
20
N.A.
6.6
13.3
N.A.
20
26.6
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
20
20
N.A.
20
33.3
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
10
30
40
40
30
30
10
30
40
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
30
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
50
30
10
10
0
10
20
10
10
20
10
0
0
0
% G
% His:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
40
% N
% Pro:
30
0
0
20
0
30
30
20
50
0
0
50
90
50
10
% P
% Gln:
0
0
10
0
10
0
0
10
0
0
40
30
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
0
0
40
30
0
0
0
0
% S
% Thr:
0
10
0
0
20
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
30
0
0
0
10
30
30
0
0
10
0
0
50
40
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _