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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP4X1 All Species: 15.76
Human Site: Y112 Identified Species: 49.52
UniProt: Q8N118 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N118 NP_828847.1 509 58875 Y112 R T D P K S Q Y L Q K F S P P
Chimpanzee Pan troglodytes XP_513386 509 58903 Y112 R T D P K S Q Y L Q K F S P P
Rhesus Macaque Macaca mulatta XP_001109193 508 58220 Y111 R T D P K S Q Y L Q K F L P P
Dog Lupus familis XP_539622 507 58744 Y112 R T D P K S K Y L Y K F L I P
Cat Felis silvestris
Mouse Mus musculus O88833 509 58321 G117 R S D P K A N G A Y R L L A P
Rat Rattus norvegicus Q8K4D6 507 58555 Y112 R T D P K T Q Y L H Q L M T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422455 504 57538 V115 R G D P K P P V P Y Q F L V P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27589 501 57896 N101 Q Q H I T K N N L Y K L L N C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 86 74 N.A. 50 69.7 N.A. N.A. 48.5 N.A. N.A. N.A. 32 N.A. N.A. N.A.
Protein Similarity: 100 99.8 88.6 85.4 N.A. 70.3 83.5 N.A. N.A. 66.5 N.A. N.A. N.A. 51.8 N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 73.3 N.A. 33.3 60 N.A. N.A. 40 N.A. N.A. N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 80 N.A. 53.3 73.3 N.A. N.A. 46.6 N.A. N.A. N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 13 0 0 13 0 0 0 0 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % C
% Asp: 0 0 88 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 63 0 0 0 % F
% Gly: 0 13 0 0 0 0 0 13 0 0 0 0 0 0 0 % G
% His: 0 0 13 0 0 0 0 0 0 13 0 0 0 0 0 % H
% Ile: 0 0 0 13 0 0 0 0 0 0 0 0 0 13 0 % I
% Lys: 0 0 0 0 88 13 13 0 0 0 63 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 75 0 0 38 63 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % M
% Asn: 0 0 0 0 0 0 25 13 0 0 0 0 0 13 0 % N
% Pro: 0 0 0 88 0 13 13 0 13 0 0 0 0 38 88 % P
% Gln: 13 13 0 0 0 0 50 0 0 38 25 0 0 0 0 % Q
% Arg: 88 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % R
% Ser: 0 13 0 0 0 50 0 0 0 0 0 0 25 0 0 % S
% Thr: 0 63 0 0 13 13 0 0 0 0 0 0 0 13 0 % T
% Val: 0 0 0 0 0 0 0 13 0 0 0 0 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 63 0 50 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _