KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMP21
All Species:
5.45
Human Site:
S142
Identified Species:
15
UniProt:
Q8N119
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N119
NP_671724.1
569
65015
S142
G
P
P
P
R
A
R
S
R
R
S
P
R
A
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085506
569
64889
S142
G
P
P
P
R
A
R
S
R
R
S
P
R
A
P
Dog
Lupus familis
XP_854180
552
62802
F130
A
P
P
R
P
K
R
F
L
P
P
P
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3F2
568
65436
A141
S
L
G
L
R
P
R
A
R
Q
K
R
F
L
Q
Rat
Rattus norvegicus
Q499S5
491
55493
K100
L
N
A
R
N
R
Q
K
R
F
V
L
S
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516526
488
55007
T97
P
S
A
F
S
R
R
T
L
R
W
R
L
V
G
Chicken
Gallus gallus
XP_415092
592
66478
M153
H
D
T
V
R
A
L
M
Y
Y
A
L
K
V
W
Frog
Xenopus laevis
O93470
604
70128
R177
N
P
D
P
P
K
I
R
R
K
R
F
L
D
M
Zebra Danio
Brachydanio rerio
XP_001342721
599
68868
V168
N
H
E
H
Q
A
P
V
R
K
K
R
H
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.6
77.5
N.A.
77.8
21.4
N.A.
52.3
20.7
57.1
50.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
97.3
85
N.A.
86.4
33.2
N.A.
65.1
34.7
70.6
65.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
33.3
N.A.
20
6.6
N.A.
13.3
13.3
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
33.3
N.A.
33.3
13.3
N.A.
20
26.6
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
23
0
0
45
0
12
0
0
12
0
0
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
12
0
0
0
0
0
0
0
0
0
0
12
0
% D
% Glu:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
12
0
0
0
12
0
12
0
12
12
0
0
% F
% Gly:
23
0
12
0
0
0
0
0
0
0
0
0
0
12
23
% G
% His:
12
12
0
12
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
23
0
12
0
23
23
0
12
0
0
% K
% Leu:
12
12
0
12
0
0
12
0
23
0
0
23
23
23
0
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
12
% M
% Asn:
23
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
45
34
34
23
12
12
0
0
12
12
34
12
12
34
% P
% Gln:
0
0
0
0
12
0
12
0
0
12
0
0
0
0
12
% Q
% Arg:
0
0
0
23
45
23
56
12
67
34
12
34
23
0
0
% R
% Ser:
12
12
0
0
12
0
0
23
0
0
23
0
12
0
12
% S
% Thr:
0
0
12
0
0
0
0
12
0
0
0
0
0
0
0
% T
% Val:
0
0
0
12
0
0
0
12
0
0
12
0
0
23
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
12
% W
% Tyr:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _