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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPTOR All Species: 26.36
Human Site: T954 Identified Species: 52.73
UniProt: Q8N122 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N122 NP_065812.1 1335 149038 T954 H K S F I S A T V Q T G F C D
Chimpanzee Pan troglodytes XP_001161716 1335 149161 T954 H K S F I S A T V Q T G F C D
Rhesus Macaque Macaca mulatta XP_001110471 1335 148870 T954 H K S F I S A T V Q T G F C D
Dog Lupus familis XP_850487 1335 149172 T954 H R S F V S A T T Q T G F C D
Cat Felis silvestris
Mouse Mus musculus Q8K4Q0 1335 149453 S954 H K S F I C A S M Q T G F C D
Rat Rattus norvegicus NP_001127971 1335 149475 T954 H K S F I C A T M Q T G F C D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426232 1335 149895 T954 H K S F I S A T V Q T G F C D
Frog Xenopus laevis NP_001088177 1334 149513 G952 V H K N F A V G S F Q T G F C
Zebra Danio Brachydanio rerio XP_001919288 1332 149175 Q954 S F V S L S L Q T G L C D W S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624060 1279 144157 Q907 W S C A Q F A Q P V S L E T E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002323654 1366 149968 L979 G G T E R S L L P Q S T I Y K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38873 1557 177591 G1110 T S K K G P S G L Y L L N G N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.8 95.9 N.A. 96.5 96.7 N.A. N.A. 95 90.5 87.9 N.A. N.A. 55.5 N.A. N.A.
Protein Similarity: 100 99.5 99.1 98.3 N.A. 98.4 98.5 N.A. N.A. 97.6 95.9 94.6 N.A. N.A. 70.4 N.A. N.A.
P-Site Identity: 100 100 100 80 N.A. 80 86.6 N.A. N.A. 100 0 6.6 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 100 6.6 13.3 N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: 40.8 N.A. N.A. N.A. 34.2 N.A.
Protein Similarity: 58.2 N.A. N.A. N.A. 51 N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 9 67 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 9 0 0 17 0 0 0 0 0 9 0 59 9 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 59 % D
% Glu: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 9 % E
% Phe: 0 9 0 59 9 9 0 0 0 9 0 0 59 9 0 % F
% Gly: 9 9 0 0 9 0 0 17 0 9 0 59 9 9 0 % G
% His: 59 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 50 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 0 50 17 9 0 0 0 0 0 0 0 0 0 0 9 % K
% Leu: 0 0 0 0 9 0 17 9 9 0 17 17 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 9 % N
% Pro: 0 0 0 0 0 9 0 0 17 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 9 0 0 17 0 67 9 0 0 0 0 % Q
% Arg: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 17 59 9 0 59 9 9 9 0 17 0 0 0 9 % S
% Thr: 9 0 9 0 0 0 0 50 17 0 59 17 0 9 0 % T
% Val: 9 0 9 0 9 0 9 0 34 9 0 0 0 0 0 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _