KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM177A1
All Species:
16.97
Human Site:
T181
Identified Species:
41.48
UniProt:
Q8N128
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N128
NP_001072987.1
213
23757
T181
V
Q
T
D
Q
P
E
T
V
I
S
S
S
F
V
Chimpanzee
Pan troglodytes
XP_510231
325
35466
T293
V
Q
T
D
Q
P
E
T
V
I
S
S
S
F
V
Rhesus Macaque
Macaca mulatta
XP_001083415
235
26079
T203
V
Q
T
D
Q
P
E
T
V
I
S
S
S
F
V
Dog
Lupus familis
XP_536150
173
19823
G142
R
C
H
L
E
A
R
G
Q
E
Y
G
T
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BR63
207
23560
T176
V
Q
T
D
Q
P
E
T
V
S
S
S
F
V
N
Rat
Rattus norvegicus
XP_002729670
209
23751
T177
V
Q
T
D
Q
P
E
T
V
V
S
S
S
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512078
198
22486
A165
V
H
K
E
Q
P
E
A
M
S
S
S
S
F
V
Chicken
Gallus gallus
NP_001026373
213
23955
A181
V
Q
T
E
Q
P
E
A
T
T
S
T
S
F
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001099177
205
23570
E174
Q
P
K
T
E
Q
P
E
A
T
A
S
F
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787031
219
24349
L179
E
K
E
E
K
E
E
L
D
R
Q
M
A
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.9
85.5
29.1
N.A.
84
82.6
N.A.
67.1
72.3
N.A.
53.9
N.A.
N.A.
N.A.
N.A.
34.2
Protein Similarity:
100
65.2
87.6
48.8
N.A.
89.6
88.7
N.A.
77.4
82.6
N.A.
70.8
N.A.
N.A.
N.A.
N.A.
54.3
P-Site Identity:
100
100
100
0
N.A.
73.3
93.3
N.A.
60
66.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
73.3
100
N.A.
73.3
80
N.A.
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
20
10
0
10
0
10
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
50
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
10
0
10
30
20
10
80
10
0
10
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
20
60
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% G
% His:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
30
0
0
0
0
0
% I
% Lys:
0
10
20
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% N
% Pro:
0
10
0
0
0
70
10
0
0
0
0
0
0
0
0
% P
% Gln:
10
60
0
0
70
10
0
0
10
0
10
0
0
0
10
% Q
% Arg:
10
0
0
0
0
0
10
0
0
10
0
0
0
10
10
% R
% Ser:
0
0
0
0
0
0
0
0
0
20
70
70
60
0
0
% S
% Thr:
0
0
60
10
0
0
0
50
10
20
0
10
10
0
0
% T
% Val:
70
0
0
0
0
0
0
0
50
10
0
0
0
20
60
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _