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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LGI4
All Species:
12.73
Human Site:
S341
Identified Species:
40
UniProt:
Q8N135
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N135
NP_644813.1
537
59141
S341
A
D
A
S
K
A
G
S
T
T
L
L
C
R
D
Chimpanzee
Pan troglodytes
Q1EGL2
557
63773
F356
A
D
S
S
K
A
G
F
T
T
I
Y
K
W
N
Rhesus Macaque
Macaca mulatta
XP_001106283
675
75127
A480
A
D
S
S
K
A
G
A
T
S
L
Y
R
W
H
Dog
Lupus familis
XP_541696
534
58818
S338
A
D
A
S
K
A
G
S
T
T
L
L
C
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1S1
537
59358
S341
A
D
A
S
K
A
G
S
T
T
L
L
C
R
D
Rat
Rattus norvegicus
Q8K4Y5
557
63709
F356
A
D
S
S
K
A
G
F
T
T
I
Y
K
W
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001038120
526
60552
F331
A
D
S
S
K
A
G
F
T
T
V
Y
K
W
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001122241
543
62031
S348
A
D
S
S
K
A
G
S
T
T
V
Y
K
W
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.9
35.1
94
N.A.
88.4
48.1
N.A.
N.A.
47.4
N.A.
48.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
65.8
50.2
96.6
N.A.
93.4
65.8
N.A.
N.A.
64.9
N.A.
68.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
53.3
93.3
N.A.
100
53.3
N.A.
N.A.
53.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
73.3
100
N.A.
100
73.3
N.A.
N.A.
73.3
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
100
0
38
0
0
100
0
13
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
38
0
0
% C
% Asp:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
38
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
38
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% I
% Lys:
0
0
0
0
100
0
0
0
0
0
0
0
50
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
50
38
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
13
25
0
% R
% Ser:
0
0
63
100
0
0
0
50
0
13
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
100
88
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
63
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
63
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _